Vardenafil Impurity 4 CAS 454426-80-3
| CAS No. | 454426-80-3 |
| Molecular Formula | C8H13NO4 |
| Molecular Weight | 187.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Vardenafil Impurity 4 (CAS 454426-80-3) is a high-purity analytical reference standard with the molecular formula C8H13NO4 and a molecular weight of 187.19 g/mol.
Structurally, Vardenafil Impurity 4 (C8H13NO4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 187.19 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H13NO4 |
| Molecular Weight | 187.19 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Vardenafil Standards
- Vardenafil Impurity 20 (CAS 879-57-2)
- Vardenafil Impurity 7 (CAS 53623-81-7)
- Vardenafil Impurity 18 (CAS 68282-26-8)
- Vardenafil Impurity 8 (CAS 224789-20-2)
- Vardenafil Impurity 46 (CAS 1417529-59-9)
- Vardenafil Impurity 21 (Mixture of E/Z-Isomers) (CAS 68282-25-7)
- Vardenafil Impurity 51 (CAS CATO-C4X-101751)
- Vardenafil Impurity 52 (CAS 224789-22-4)
Recommended Standards
- tert-butyl 4-oxo-1,2-oxazolidine-2-carboxylate (CAS 2031259-21-7)
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- 2-(4-Bromophenyl)-3,8-dimethylquinoline-4-carboxylic acid (CAS 522594-92-9)
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- 2-(4-tert-Butylphenyl)-5-(4-biphenylyl)-1,3,4-oxadiazole (purified by sublimation) (CAS 15082-28-7)
- 5-(Butylthio)-1H-1,2,4-triazol-3-amine (CAS 79741-85-8)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
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