Vardenafil Impurity 20 CAS 879-57-2
| CAS No. | 879-57-2 |
| Molecular Formula | C9H12N2O2 |
| Molecular Weight | 180.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Vardenafil Impurity 20 (CAS 879-57-2, C9H12N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Vardenafil Impurity 20 (C9H12N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Vardenafil Impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H12N2O2 |
| Molecular Weight | 180.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Vardenafil Standards
- Vardenafil Impurity 4 (CAS 454426-80-3)
- Vardenafil Impurity 7 (CAS 53623-81-7)
- Vardenafil Impurity 18 (CAS 68282-26-8)
- Vardenafil Impurity 8 (CAS 224789-20-2)
- Vardenafil Impurity 46 (CAS 1417529-59-9)
- Vardenafil Impurity 21 (Mixture of E/Z-Isomers) (CAS 68282-25-7)
- Vardenafil Impurity 51 (CAS CATO-C4X-101751)
- Vardenafil Impurity 52 (CAS 224789-22-4)
Recommended Standards
- Apremilast Impurity 108 (CAS 120-25-2)
- (2R,3S)-3-amino-2-hydroxy-3-phenylpropanamide (CAS CATO-C4X-111546)
- 2-(3,4-Dimethoxyphenyl)acetaldehyde (CAS 5703-21-9)
- Bisoprolol Impurity 37 (CAS 4204-78-8)
- Gadobutrol Impurity N5 (CAS 112193-75-6)
- Rebamipide Impurity 32 (CAS CATO-C4X-152332)
- Sertraline Impurity 70 (CAS CATO-C4X-134470)
- 1-(3-(Thiophen-2-yl)-1,2,4-oxadiazol-5-yl)ethan-1-amine (CAS 937654-30-3)
- RH 155 (CAS 254451-42-8)
- (1-(3-Chloro-4-fluorophenyl)-1H-1,2,3-triazol-4-yl)(4-fluorophenyl)methanone (CAS 444151-90-0)
- 9-Bromo-2-iodo-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine (CAS 1282516-69-1)
- 5-Methylpyridine-3-carboxamide (CAS 70-57-5)
- Methyl 1-methylphosphinane-4-carboxylate 1-oxide (CAS 2713862-42-9)
- α Bag Cell Peptide (1-9) (CAS 87549-52-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com