((2R,3S,5R)-5-(2,6-Diamino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate CAS 4546-60-5
| CAS No. | 4546-60-5 |
| Molecular Formula | C10H15N6O6P |
| Molecular Weight | 346.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
((2R,3S,5R)-5-(2,6-Diamino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 4546-60-5) is a high-purity analytical reference standard with the molecular formula C10H15N6O6P and a molecular weight of 346.24 g/mol.
Structurally, ((2R,3S,5R)-5-(2,6-Diamino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate (C10H15N6O6P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.5, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 346.24 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H15N6O6P |
| Molecular Weight | 346.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 6 |
Recommended Standards
- ((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen phosphoramidate (CAS 6154-31-0)
- 2-((4-Bromophenyl)thio)-1-methyl-1H-indole-3-carbaldehyde (CAS 338416-15-2)
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- 2-((4'-(Tert-butyl)-[1,1'-biphenyl]-4-yl)oxy)acetic acid (CAS 1181237-40-0)
- 5-Bromo-2-isopropylbenzofuran (CAS 19019-23-9)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
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