455-16-3 4-Toluenesulfonyl fluoride Benzenesulfonyl fluoride, 4-methyl- 4-Methylbenzenesulfonyl fluoride p-Toluenesulfonyl fluoride p-Toluenesulphonyl fluoride 4-11-00-00375 (Beilstein Handbook Reference) BRN 2208423 EINECS 207-238-6 p-Methylbenzenesulfonyl fluoride p-Methylphenylsulfonyl fluoride NSC 2749 Phenylmethylsulfonyl fluoride Toluene-4-sulfonyl fluoride Toluene-p-sulphonyl fluoride 4-Tolylsulfonyl fluoride Tosyl fluoride CAS 455-16-3
| CAS No. | 455-16-3 |
| Molecular Formula | C7H13FO2S |
| Molecular Weight | 180.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 455-16-3 4-Toluenesulfonyl fluoride Benzenesulfonyl fluoride, 4-methyl- 4-Methylbenzenesulfonyl fluoride p-Toluenesulfonyl fluoride p-Toluenesulphonyl fluoride 4-11-00-00375 (Beilstein Handbook Reference) BRN 2208423 EINECS 207-238-6 p-Methylbenzenesulfonyl fluoride p-Methylphenylsulfonyl fluoride NSC 2749 Phenylmethylsulfonyl fluoride Toluene-4-sulfonyl fluoride Toluene-p-sulphonyl fluoride 4-Tolylsulfonyl fluoride Tosyl fluoride (CAS 455-16-3), a certified reference material (molecular formula C7H13FO2S, MW 180.24 g/mol) for analytical method development and quality control.
Structurally, 455-16-3 4-Toluenesulfonyl fluoride Benzenesulfonyl fluoride, 4-methyl- 4-Methylbenzenesulfonyl fluoride p-Toluenesulfonyl fluoride p-Toluenesulphonyl fluoride 4-11-00-00375 (Beilstein Handbook Reference) BRN 2208423 EINECS 207-238-6 p-Methylbenzenesulfonyl fluoride p-Methylphenylsulfonyl fluoride NSC 2749 Phenylmethylsulfonyl fluoride Toluene-4-sulfonyl fluoride Toluene-p-sulphonyl fluoride 4-Tolylsulfonyl fluoride Tosyl fluoride (C7H13FO2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 180.24 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 455-16-3 4-Toluenesulfonyl fluoride Benzenesulfonyl fluoride, 4-methyl- 4-Methylbenzenesulfonyl fluoride p-Toluenesulfonyl fluoride p-Toluenesulphonyl fluoride 4-11-00-00375 (Beilstein Handbook Reference) BRN 2208423 EINECS 207-238-6 p-Methylbenzenesulfonyl fluoride p-Methylphenylsulfonyl fluoride NSC 2749 Phenylmethylsulfonyl fluoride Toluene-4-sulfonyl fluoride Toluene-p-sulphonyl fluoride 4-Tolylsulfonyl fluoride Tosyl fluoride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H13FO2S |
| Molecular Weight | 180.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Toluenesulfonyl Standards
- 4-Toluenesulfonyl cyanide (CAS 19158-51-1)
- p-Toluenesulfonyl Hydrazide (CAS 1576-35-8)
- o-Toluenesulfonyl Chloride (contains ca. 23% isomer) (CAS 133-59-5)
- p-Toluenesulfonyl Chloride (CAS 98-59-9)
- m-toluenesulfonyl chloride (CAS 1899-93-0)
- p-Toluenesulfonyl isocyanate (CAS 4083-64-1)
- 1-(p-Toluenesulfonyl)aziridine 1-(p-Toluenesulfonyl)ethylenimine 1-(p-Tolylsulfonyl)aziridine 1-Tosylaziridine 1-[(4-Methylphenyl)sulfonyl]aziridine 3634-89-7 N-(p-Toluenesulfonyl)aziridine N-(p-Tolylsulfonyl)aziridine N-Tosylaziridine N-[(4-Methylphenyl)sulfonyl]aziridine N-p-Tosylaziridine (CAS 3634-89-7)
- 1-(P-Toluenesulfonyl)pyrrole-2-aldehyde (CAS 102619-05-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com