Benzoic Acid Impurity 10 CAS 455-24-3
| CAS No. | 455-24-3 |
| Molecular Formula | C8H6F2O2 |
| Molecular Weight | 172.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Benzoic Acid Impurity 10 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 172.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Benzoic Acid Impurity 10 (CAS 455-24-3) is a certified pharmaceutical impurity reference standard with the molecular formula C8H6F2O2 and a molecular weight of 172.13 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Benzoic Acid Impurity 10 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6F2O2 |
| Molecular Weight | 172.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Benzoic Standards
- 25081-39-4 Benzoic acid, 3,5-dimethyl-, methyl ester Methyl 3,5-dimethylbenzoate (CAS 25081-39-4)
- 4892-02-8 Benzoic acid, o-mercapto-, methyl ester Benzoic acid, 2-mercapto-, methyl ester 4-10-00-00280 (Beilstein Handbook Reference) AI3-26181 BRN 0956859 2-(Methoxycarbonyl)thiophenol Methyl o-mercaptobenzoate Methyl 2-mercaptobenzoate Methyl thiosalicylate Methyl-o-mercaptobenzoate NSC 30156 USAF MA-15 (CAS 4892-02-8)
- Benzoic acid, 4-(1-methylethenyl)-, methyl ester (CAS 26581-23-7)
- Benzoic acid, 4-ethenyl-2-methyl-, methyl ester (CAS 943847-34-5)
- 536-40-3 Benzoic acid, p-chloro-, hydrazide (8CI) Benzoic acid, 4-chloro-, hydrazide (9CI) 4-Chlorobenzohydrazide p-Chlorobenzhydrazide 4-Chlorobenzhydrazide p-Chlorobenzohydrazide p-Chlorobenzoic acid, hydrazide 4-Chlorobenzoic acid, hydrazide p-Chlorobenzoic hydrazide p-Chlorobenzoyl hydrazide 4-Chlorobenzoyl hydrazide p-Chlorobenzoylhydrazine 4-Chlorobenzoylhydrazine EINECS 208-632-0 NSC 54990 (CAS 536-40-3)
- 6627-91-4 Benzoic acid, 2-(cyanomethyl)- 2-(Cyanomethyl)benzoic acid 3-09-00-04267 (Beilstein Handbook Reference) BRN 0472769 o-Carboxyphenylacetonitrile alpha-Cyano-o-toluic acid EINECS 229-602-3 o-Toluic acid, alpha-cyano- (CAS 6627-91-4)
- Benzoic Acid Isobutyl Ester (CAS 120-50-3)
- Benzoic acid, 4-(1-fluoroethenyl)-, methyl ester (CAS 201606-59-9)
Recommended Standards
- 2,6-difluoro-4-methylbenzoic acid (CAS 1201597-23-0)
- Ethyl Paraben-13C6 (CAS CATO-CCFD201104)
- methyl 2,4-difluorobenzoate (CAS CATO-C3D-263298)
- Sitagliptin Impurity 80 (CAS 658-93-5)
- Remimazolam Impurity 11 (CAS CATO-C4X-282311)
- Relebactam Impurity 142 (CAS CATO-C4X-2144142)
- Ropivacaine Impurity 26 (CAS CATO-C4X-175326)
- (2-Fluoro-4,6-dimethoxyphenyl)boronic acid (CAS 309977-93-3)
- N-(Furan-2-ylmethyl)-2-(4-phenoxyphenoxy)acetamide (CAS 330677-31-1)
- 4-(4-Hexylbenzoyl)phenyl acetate (CAS 890099-79-3)
- 1-Butyl-5-methyl-1h-pyrazole (CAS 1007518-48-0)
- 2-(4-Methoxyphenyl)-5-(octylsulfanyl)-1,3,4-oxadiazole (CAS 477857-32-2)
- 2-(Methylthio)spiro[3.6]decane-2-carboxylic acid (CAS 1493496-00-6)
- Acetyl Hexapeptide-38 (CAS 1400634-44-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com