Sitagliptin Impurity 80 CAS 658-93-5
| CAS No. | 658-93-5 |
| Molecular Formula | C8H6F2O2 |
| Molecular Weight | 172.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Sitagliptin Impurity 80 (C8H6F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Sitagliptin Impurity 80 (CAS 658-93-5) is a high-purity analytical reference standard with the molecular formula C8H6F2O2 and a molecular weight of 172.13 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6F2O2 |
| Molecular Weight | 172.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Sitagliptin Standards
- Sitagliptin Impurity 79 (CAS 81228-09-3)
- Sitagliptin Impurity 78 (CAS 85068-27-5)
- Sitagliptin Impurity 67 (CAS CATO-C4X-114467)
- Sitagliptin Impurity 126 (CAS 1555495-76-5)
- Sitagliptin Impurity 163 (CAS 2945884-76-2)
- Sitagliptin Impurity 107 (CAS 89124-06-1)
- Sitagliptin Impurity 62 (CAS 723286-98-4)
- Sitagliptin Impurity 80 (CAS 220199-85-9)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com