Remimazolam Impurity 11 CAS CATO-C4X-282311
| CAS No. | CATO-C4X-282311 |
| Molecular Formula | C20H23BrN4O3 |
| Molecular Weight | 447.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Remimazolam Impurity 11 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Remimazolam Impurity 11 (CAS CATO-C4X-282311) is a certified pharmaceutical impurity reference standard with the molecular formula C20H23BrN4O3 and a molecular weight of 447.33 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution, Remimazolam Impurity 11 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 447.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H23BrN4O3 |
| Molecular Weight | 447.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Remimazolam Standards
- Remimazolam Impurity 14 (CAS CATO-C4X-282314)
- Remimazolam Impurity 12 (CAS 308243-65-4)
- Remimazolam Impurity 10 (CAS CATO-C4X-282310)
- Remimazolam Impurity 13 (CAS CATO-C4X-282313)
- Remimazolam Impurity 17 (CAS CATO-C4X-282317)
- Remimazolam Impurity 2 (CAS 960305-91-3)
- Remimazolam Impurity 5 (CAS 1276185-51-3)
- Remimazolam Impurity 1 (CAS 1275616-59-5)
Recommended Standards
- E5B7C16LFK 22619-35-8 Tioclomarol Tioclomarol [INN:DCF] 3-(5-Chloro-alpha-(p-chloro-beta-hydroxyphenethyl)-2-thenyl)-4-hydroxycoumarin EINECS 245-132-1 Tioclomarolum [INN-Latin] Tioclomarolum UNII-E5B7C16LFK (CAS 22619-35-8)
- 5-((7-(TRIFLUOROMETHYL)-5-(4-(TRIFLUOROMETHYL)PHENYL)PYRAZOLO[1,5-A]PYRIMIDIN-3-YL)ETHYNYL)PYRIDIN-2-AMINE (CAS 911115-16-7)
- 3-(2,4-Dichlorophenoxy)-6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophene 1-oxide (CAS 477762-76-8)
- Remdesivir Impurity 32 (CAS CATO-C4X-210032)
- Carbazochrome Impurity N6 (CAS 25574-55-4)
- Bromocriptine EP Impurity C (CAS 65700-36-9)
- Ceftazidime Impurity 27 (CAS 83654-89-1)
- Gabapentin Impurity 38 (CAS 3048030-55-0)
- N-Butyl-N-methylpyrrolidin-3-amine (CAS 713141-69-6)
- 3,5-Bis(3,4-dimethoxyphenyl)-2,2-dimethyl-2,5-dihydrofuran (CAS 92532-88-2)
- 1-Benzyl-4-(4-methoxyphenoxy)phthalazine (CAS 338404-26-5)
- 1-Chloroacetone (CAS 78-95-5)
- Z-Asp(OMe)-OtBu (CAS 60079-12-1)
- Gastrin Tetrapeptide (CAS 1947-37-1)
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