Econazole Impurity 12 CAS 45892-47-5
| CAS No. | 45892-47-5 |
| Molecular Formula | C8H5Cl3 |
| Molecular Weight | 207.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 207.48 g/mol gives Econazole Impurity 12 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Econazole Impurity 12 (CAS 45892-47-5) is a certified pharmaceutical impurity reference standard with the molecular formula C8H5Cl3 and a molecular weight of 207.48 g/mol.
Econazole Impurity 12 (C8H5Cl3) contains chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Econazole Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl3 |
| Molecular Weight | 207.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1970 |
| Halogen Content | Cl-containing |
Related Econazole Standards
- Econazole Impurity 8 (CAS 14866-28-5)
- Econazole Impurity 13 (CAS 88965-93-9)
- Econazole Impurity 4 (CAS 137958-96-4)
- Econazole impurity 27 (CAS 27087-94-1)
- Econazole impurity 29 (CAS 24155-32-6)
- Econazole impurity 17 (CAS 24155-44-0)
- Econazole impurity 18 (CAS 24155-45-1)
- Econazole Impurity 11 (CAS 4252-78-2)
Recommended Standards
- 1,2,4-Trichloro-5-vinylbenzene (CAS 1835-89-8)
- zinc acrylate (CAS 14643-87-9)
- 1,3,5-Trichloro-2-vinylbenzene (CAS 15270-64-1)
- 4-Chloro-6-(trifluoromethyl)pyrimidine-5-carbonitrile (CAS 1402551-79-4)
- Apremilast impurity 64 (CAS CATO-C4X-100964)
- Carvedilol Impurity 35 (CAS 1187921-93-2)
- Tegoprazan Impurity 127 (CAS CATO-C4X-2297127)
- 1-(5-Bromo-2-methylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1537447-67-8)
- 2-((Methylsulfonyl)thio)ethyl 4-aminobenzoate (CAS 212207-24-4)
- 2-(Chloromethyl)-3,4-dibromo-6-(difluoromethyl)pyridine (CAS 1806808-31-0)
- 1-Methyl-1H-imidazol-4-carbohydrazide (CAS 41064-93-1)
- N-(2-chloro-4-pivaloylpyridin-3-yl)pivalamide (CAS 1951444-95-3)
- (4-(Propylsulfonyl)phenyl)boronic acid (CAS 1217501-34-2)
- Liraglutide (14-31)TFA Salt (CAS CATO-C4X-19927)
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