Paliperidone Impurity 129 CAS 46020-63-7

Description

Compared with other compounds in its class, the molecular weight of 194.16 g/mol gives Paliperidone Impurity 129 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Paliperidone Impurity 129 (CAS 46020-63-7), a pharmacopoeial impurity reference standard (molecular formula C6H4F2O3S, MW 194.16 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Paliperidone Impurity 129 (C6H4F2O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Paliperidone Impurity 129 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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