1-Bromo-3,5-difluorobenzene CAS 461-96-1
| CAS No. | 461-96-1 |
| Molecular Formula | C6H3BrF2 |
| Molecular Weight | 192.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-Bromo-3,5-difluorobenzene is closely related to fluorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-Bromo-3,5-difluorobenzene (CAS 461-96-1), a certified reference material (molecular formula C6H3BrF2, MW 192.99 g/mol) for analytical method development and quality control.
Structurally, 1-Bromo-3,5-difluorobenzene (C6H3BrF2) contains fluorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 192.99 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Bromo-3,5-difluorobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H3BrF2 |
| Molecular Weight | 192.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 1-Bromo-2,3-difluorobenzene (CAS 38573-88-5)
- 1-Bromo-2,4-difluorobenzene (CAS 348-57-2)
- 2-Bromo-1,4-difluorobenzene (CAS 399-94-0)
- 1-Bromo-3,4-difluorobenzene (CAS 348-61-8)
- 3-Bromo-4,5-dihydroisoxazole-5-carboxylic acid amide (CAS 1030613-69-4)
- 5-Bromo-1-methylimidazolidine-2,4-dione (CAS 113259-78-2)
- 2-(5-Bromo-1,3,4-oxadiazol-2-yl)ethan-1-ol (CAS 1781571-30-9)
- 4-Bromo-5-methoxyfuran-2(5H)-one (CAS 62594-18-7)
Recommended Standards
- 5,6-Dichloropyrimidine-4-carboxylic acid (CAS 914916-97-5)
- 5,6-Dichloropyrazine-2-carboxylic acid (CAS 76537-42-3)
- 3,4-Dichloro-5-fluorobenzaldehyde (CAS 1160574-74-2)
- 4,6-Dichloropyrimidine-2-carboxylic acid (CAS 684220-30-2)
- 3-Bromo-DL-phenylalanine (CAS 30163-20-3)
- [2,2'-Bipyridine]-4-carbaldehyde (CAS 146581-82-0)
- Methyl 4-Bromo-3-chloropyrrole-2-carboxylate (CAS 1629633-72-2)
- 3-Propoxybenzohydrazide (CAS 350988-61-3)
- Actyl octylcarbamate (CAS 1071-65-4)
- 5-Chloro-2-methylpyridine-3-sulfonyl chloride (CAS 1515362-51-2)
- 3,5-Bis(perfluorohexyl)-1-(trifluoroacetyl)-1H- pyrazole (CAS 261761-08-4)
- 4-Amino-N,1-dimethyl-1H-pyrazole-3-carboxamide (CAS 1001500-41-9)
- Tert-butyl 7-fluoro-2,5-diazaspiro[3.4]Octane-5-carboxylate (CAS 2306265-68-7)
- Tirzepatide Impurity 16 (CAS CATO-C4X-324016)
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