Dapagliflozin Impurity 27 CAS 461432-25-7
| CAS No. | 461432-25-7 |
| Molecular Formula | C29H33ClO10 |
| Molecular Weight | 577.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Dapagliflozin Impurity 27 (CAS 461432-25-7), a pharmacopoeial impurity reference standard (molecular formula C29H33ClO10, MW 577.02 g/mol) used for the identification and quantification of trace impurities in APIs.
Dapagliflozin Impurity 27 (C29H33ClO10) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Dapagliflozin Impurity 27 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H33ClO10 |
| Molecular Weight | 577.02 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
Related Dapagliflozin Standards
- Dapagliflozin Impurity 106 (CAS CATO-C4X-1138106)
- Dapagliflozin Impurity 125 (CAS CATO-C4X-1138125)
- Dapagliflozin Impurity 14 (CAS CATO-C4X-113814)
- Dapagliflozin Impurity 150 (CAS 1469910-84-6)
- Dapagliflozin Impurity 155 (CAS CATO-C4X-1138155)
- Dapagliflozin Impurity 158 (CAS CATO-C4X-1138158)
- Dapagliflozin Impurity 177 (CAS CATO-C4X-1138177)
- Dapagliflozin Impurity 21 (CAS CATO-C4X-113821)
Recommended Standards
- Dapagliflozin impurity 215 (CAS CATO-C4X-1138215)
- Dapagliflozin Impurity 53 (CAS CATO-C4X-113853)
- Dapagliflozin Impurity 94 (CAS CATO-C4X-113894)
- Dapagliflozin Impurity 99 (CAS CATO-C4X-113899)
- Mirabegron Impurity 48 (CAS CATO-C4X-103248)
- Talazoparib Impurity 2 (CAS CATO-C4X-33732)
- Chlorthalidone impurity 19 (CAS CATO-C4X-158519)
- 1-[4-(Dimethylamino)-2-hydroxyphenyl]ethan-1-one (CAS 107070-69-9)
- 4-Ethyl-3-(trifluoromethyl)-1,2-oxazol-5-amine (CAS 166964-41-6)
- [4-(2-Oxo-imidazolidin-1-yl)-phenyl]-acetic acid (CAS 492445-92-8)
- Methyl 3-(2,5-dimethyl-1H-pyrrol-1-yl)-3-(4-fluorophenyl)propanoate (CAS 866050-70-6)
- 4-Ethyl-5-methyl-3-phenyl-4,5-dihydroisoxazol-5-ol (CAS 449181-14-0)
- (R)-a-Amino-3,4-dimethoxybenzeneacetic acid (CAS 117446-20-5)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com