Droperidol EP Impurity D CAS 466118-75-2
| CAS No. | 466118-75-2 |
| Molecular Formula | C22H22FN3O3 |
| Molecular Weight | 395.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Droperidol EP Impurity D.
As a process- or degradation-related impurity, Droperidol EP Impurity D (CAS 466118-75-2, C22H22FN3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Droperidol EP Impurity D is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 395.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Droperidol EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H22FN3O3 |
| Molecular Weight | 395.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Droperidol Standards
- Droperidol Impurity 19 (CAS CATO-C4X-276919)
- Droperidol EP Impurity B (CAS 1026015-45-1)
- Droperidol (CAS 548-73-2)
- Droperidol Impurity 17 (CAS 466118-73-0)
- Droperidol Impurity 10 (CAS CATO-C4X-276910)
- Droperidol Impurity 11 (CAS CATO-C4X-276911)
- Droperidol Impurity 7 (CAS 60373-71-9)
- Droperidol Impurity 16 (CAS 39146-45-7)
Recommended Standards
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- 3-(4-Methylphenyl)-2-{[3-(trifluoromethyl)phenyl]sulfanyl}quinoline (CAS 339102-64-6)
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- 6-Bromo-7-chloro-2,3-dihydro-1H-inden-1-one (CAS 1337850-20-0)
- Methyl 4-chloro-2-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 1393576-33-4)
- FBPase-1 Inhibitor (CAS 883973-99-7)
- Axitinib Impurity 66 (CAS 2419145-29-0)
- (2R,4S)-Benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate, 97% (CAS 205654-80-4)
- (1R)-7-(sec-butyl)-1,2,3,4-tetrahydronaphthalen-1-ol (CAS 1372898-10-6)
- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com