2-(4-Chlorophenyl)-4-(4-(trifluoromethyl)phenyl)thiomorpholine-3,5-dione 1-oxide CAS 252058-94-9
| CAS No. | 252058-94-9 |
| Molecular Formula | C17H11ClF3NO3S |
| Molecular Weight | 401.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(4-Chlorophenyl)-4-(4-(trifluoromethyl)phenyl)thiomorpholine-3,5-dione 1-oxide (CAS 252058-94-9), molecular formula C17H11ClF3NO3S and molecular weight 401.79 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-Chlorophenyl)-4-(4-(trifluoromethyl)phenyl)thiomorpholine-3,5-dione 1-oxide (C17H11ClF3NO3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 2-(4-Chlorophenyl)-4-(4-(trifluoromethyl)phenyl)thiomorpholine-3,5-dione 1-oxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H11ClF3NO3S |
| Molecular Weight | 401.79 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
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Recommended Standards
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-phenyl-1H-pyrrole-2-sulfonamide (CAS 321433-63-0)
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1-[4-(4-fluorophenyl)piperazin-1-yl]ethan-1-one (CAS 444151-88-6)
- 4-(chloromethyl)-N-{2-[2-nitro-4-(trifluoromethyl)anilino]ethyl}benzamide (CAS 303188-07-0)
- 4-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-4,5-dihydro-1H-imidazol-1-yl)benzoic acid (CAS 321433-53-8)
- Benzyl 9H-carbazole-9-carbodithioate (CAS 137780-73-5)
- (E)-3-Bromo-2-(2-nitrovinyl)thiophene (CAS 2649764-23-6)
- Ethyl 4-(3,4-difluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate (CAS 478261-60-8)
- (2,6-Dichloro-4-(difluoromethyl)pyridin-3-yl)methanol (CAS 1806894-96-1)
- Enalapril Impurity 7 (CAS CATO-C4X-13347)
- 66898-97-3 1-{[3-(Trifluoromethyl)phenyl]methyl}piperidin-4-amine DTXSID10512381 (CAS 66898-97-3)
- 5-Iodothiophene-3-carboxamide (CAS 18800-08-3)
- 2-Chloro-N-(5-(4-fluorophenyl)-1,3,4-thiadiazol-2-yl)benzamide (CAS 391226-48-5)
- Methyl 6-bromonicotinate 6-bromonicotinic acid methyl ester methyl 6-bromo-nicotinate 6-bromo-nicotinic acid methyl ester 2-bromo-5-nicotinic acid methyl ester Methyl 6-bromopyridine-3-carboxylate 6-Bromo-pyridine-3-carboxylic acid methyl ester Methyl 2-bromopyridine-5-carboxylate 26218-78-0 (CAS 26218-78-0)
- Fibrinopeptide A (human) (CAS 25422-31-5)
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