Eszopiclone Impurity 24 CAS 4744-50-7
| CAS No. | 4744-50-7 |
| Molecular Formula | C6H2N2O3 |
| Molecular Weight | 150.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Eszopiclone Impurity 24 (CAS 4744-50-7) is a certified pharmaceutical impurity reference standard with the molecular formula C6H2N2O3 and a molecular weight of 150.09 g/mol.
The molecular framework of Eszopiclone Impurity 24 (C6H2N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H2N2O3 |
| Molecular Weight | 150.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Eszopiclone Standards
- Eszopiclone Impurity 26 (CAS 7560-85-2)
- Eszopiclone Impurity 23 (CAS 43200-82-4)
- Eszopiclone Impurity 6 (CAS 1122549-43-2)
- Eszopiclone Impurity 7 (CAS 43200-83-5)
- Eszopiclone Impurity 27 (CAS 1216659-29-8)
- Eszopiclone impurity 28 Sodium salt (CAS CATO-C4X-123828)
- Eszopiclone impurity 26 (CAS 151776-26-0)
- Eszopiclone Impurity 25 (CAS 43200-88-0)
Recommended Standards
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- L-(+)-Tartaric Acid (CAS 87-69-4)
- Benzalkonium Chloride impurity 7 (CAS 14727-68-5)
- Ibrutinib Impurity 64 (CAS CATO-C4X-106464)
- Mebeverine EP Impurity F (CAS 69788-70-1)
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