Clavulanate Potassium EP Impurity A CAS 4744-51-8
| CAS No. | 4744-51-8 |
| Molecular Formula | C8H12N2O2 |
| Molecular Weight | 168.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Clavulanate Potassium EP Impurity A (CAS 4744-51-8, C8H12N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Clavulanate Potassium EP Impurity A (C8H12N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Clavulanate Potassium EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12N2O2 |
| Molecular Weight | 168.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Clavulanate Standards
- Potassium Clavulanate EP Impurity M (CAS 3033-62-3)
- Clavulanate Potassium EP Impurity D (CAS 404839-11-8)
- Potassium Clavulanate Impurity 21 (CAS CATO-C4X-114621)
- Potassium Clavulanate EP Impurity L (CAS 4013-94-9)
- Clavulanate Potassium EP Impurity C (CAS 86917-74-0)
- Potassium Clavulanate impurity 25 (CAS 128173-47-7)
- Potassium Clavulanate impurity 23 (CAS 112240-59-2)
- Potassium Clavulanate EP Impurity K (CAS 107-45-9)
Recommended Standards
- Lenvatinib Impurity 98 (CAS CATO-C4X-114098)
- Salbutamol Impurity 93 (CAS 141024-79-5)
- Levetiracetam EP Impurity B (CAS 358629-47-7)
- Bisoprolol Impurity 68 (CAS 325147-81-7)
- Tofacitinib Impurity 211 (CAS CATO-C4X-1079211)
- Entecavir Impurity 63 (CAS CATO-C4X-107763)
- Dotinurad Impurity 57 (CAS CATO-C4X-249457)
- Ethyl 3-bromo-5-ethoxy-1H-pyrazole-4-carboxylate (CAS 1207431-91-1)
- 6-Cyclopropyl-6-oxohexanoic acid (CAS 898766-89-7)
- N-(4-bromo-2-methoxyphenyl)acetamide (CAS 143360-01-4)
- 2-(2-Amino-5-methylphenyl)acetonitrile (CAS 90765-19-8)
- 2-Bromo-6-formylbenzoic acid (CAS 1245915-98-3)
- 4-Bromo-1-(difluoromethyl)-3-(ethoxymethyl)-1H-pyrazole (CAS 1856078-50-6)
- T-Peptide (CAS 2022956-62-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com