Mitoxantrone Impurity 6 CAS 476-43-7
| CAS No. | 476-43-7 |
| Molecular Formula | C15H10O6 |
| Molecular Weight | 286.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Mitoxantrone Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Mitoxantrone Impurity 6 (CAS 476-43-7, C15H10O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C15H10O6, Mitoxantrone Impurity 6 contains a flavonoid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 286.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C15H10O6 |
| Molecular Weight | 286.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Mitoxantrone Standards
- Mitoxantrone Impurity N1 (CAS 81-59-4)
- Mitoxantrone Impurity 10 (CAS 6374-78-3)
- Mitoxantrone Impurity 11 (CAS 128-94-9)
- Mitoxantrone EP Impurity A (CAS 89991-52-6)
- Mitoxantrone Impurity 26 (CAS CATO-C4X-103426)
- Mitoxantrone Impurity 25 (CAS CATO-C4X-103425)
- Mitoxantrone Impurity 16 (CAS CATO-C4X-103416)
- Mitoxantrone Impurity 17 (CAS CATO-C4X-103417)
Recommended Standards
- 4,4＇-AZOXYDIBENZOIC ACID (CAS 582-69-4)
- Diacerein Impurity 22 (CAS CATO-C4X-108122)
- Norartocarpetin (CAS 520-30-9)
- Azacitidine Impurity 24 (CAS 1174733-90-4)
- Gefitinib Impurity 33 (CAS 909863-33-8)
- Budesonide Impurity 26 (CAS 77017-17-5)
- Sivelestat sodium impurity 42 (CAS CATO-C4X-212342)
- 5-Bromo-3-cyclopropoxypicolinamide (CAS 1243458-59-4)
- methyl 3-amino-4-(4-methylphenyl)thiophene-2-carboxylate (CAS 160133-75-5)
- 3-(4-Bromophenoxy)-1-methylpyrrolidine (CAS 486422-46-2)
- 4-[5-(Azetidin-3-yl)-1,2,4-oxadiazol-3-yl]pyridine (CAS 1225227-48-4)
- 1-Phenyl-2-(pyrrolidin-1-yl)ethan-1-amine (CAS 31788-83-7)
- 3-Bromopyridine-2-sulfonamide (CAS 65938-87-6)
- D-β-Asp9-Tirzepatide (CAS CATO-CPTD788932)
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