Mitoxantrone Impurity 10 CAS 6374-78-3
| CAS No. | 6374-78-3 |
| Molecular Formula | C14H9NO5 |
| Molecular Weight | 271.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 271.22 g/mol gives Mitoxantrone Impurity 10 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Mitoxantrone Impurity 10 (CAS 6374-78-3, C14H9NO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Mitoxantrone Impurity 10 (C14H9NO5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Mitoxantrone Impurity 10 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9NO5 |
| Molecular Weight | 271.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Mitoxantrone Standards
- Mitoxantrone Impurity 11 (CAS 128-94-9)
- Mitoxantrone Impurity N1 (CAS 81-59-4)
- Mitoxantrone Impurity 6 (CAS 476-43-7)
- Mitoxantrone EP Impurity A (CAS 89991-52-6)
- Mitoxantrone Impurity 26 (CAS CATO-C4X-103426)
- Mitoxantrone Impurity 25 (CAS CATO-C4X-103425)
- Mitoxantrone Impurity 16 (CAS CATO-C4X-103416)
- Mitoxantrone Impurity 17 (CAS CATO-C4X-103417)
Recommended Standards
- 2,5-Dioxopyrrolidin-1-yl ((3R,3aS,6aR)-hexahydrofuro[2,3-B]furan-3-yl) carbonate (CAS 253265-97-3)
- BIS THF HNS Derivative 3 (CAS 799241-86-4)
- 2158-91-0 2-benzoyl-4-nitrobenzoic acid DTXSID80357867 (CAS 2158-91-0)
- Diethyl 1-methyl-4-nitro-1H-pyrazole-3,5-dicarboxylate (CAS 1002535-10-5)
- Ceritinib Impurity 22 (CAS CATO-C4X-104822)
- Bilastine Impurity 12 Formate (CAS 2099128-83-1(free base))
- Cariprazine Impurity 39 (CAS CATO-C4X-240839)
- 2-Chloro-N-(2-formylphenyl)acetamide (CAS 6141-22-6)
- Cyclopenta[d]imidazole-2,4(1H,3H)-dithione (CAS 853944-78-2)
- 2,6-Dimethyl-8-(pentan-3-yl)imidazo[1,2-b]pyridazine (CAS 910552-63-5)
- 2-(4-fluorofuran-3-yl)acetic acid (CAS 1539739-80-4)
- (2,5-Dimethoxybenzyl)triphenylphosphonium bromide (CAS 25224-32-2)
- Diosmin Impurity 10 (CAS 115960-14-0)
- Liraglutide Impurity 19 TFA Salt (CAS CATO-C4X-199219)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com