Mitoxantrone Impurity N1 CAS 81-59-4
| CAS No. | 81-59-4 |
| Molecular Formula | C14H10O6 |
| Molecular Weight | 274.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Mitoxantrone Impurity N1 (CAS 81-59-4, C14H10O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C14H10O6, Mitoxantrone Impurity N1 contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 274.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Mitoxantrone Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H10O6 |
| Molecular Weight | 274.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Mitoxantrone Standards
- Mitoxantrone Impurity 10 (CAS 6374-78-3)
- Mitoxantrone Impurity 11 (CAS 128-94-9)
- Mitoxantrone Impurity 6 (CAS 476-43-7)
- Mitoxantrone EP Impurity A (CAS 89991-52-6)
- Mitoxantrone Impurity 26 (CAS CATO-C4X-103426)
- Mitoxantrone Impurity 25 (CAS CATO-C4X-103425)
- Mitoxantrone Impurity 16 (CAS CATO-C4X-103416)
- Mitoxantrone Impurity 17 (CAS CATO-C4X-103417)
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- Levofloxacin Impurity 8 (CAS 2489671-28-3)
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- 1-(4-(Azetidin-3-yl)piperazin-1-yl)-2,2,2-trifluoroethanone (CAS 1252779-86-4)
- 2-Chloro-3,5-dimethyl-1H-indole (CAS 1352485-23-4)
- 4-[5-(3-Nitrophenyl)-1H-pyrazol-3-yl]-1-{[4-(trifluoromethyl)phenyl]methyl}piperidine (CAS 1030386-16-3)
- 2-(3-((Dimethylamino)methyl)phenyl)acetic acid (CAS 933737-02-1)
- D-[Val]10-Semaglutide (CAS CATO-CPTD788630)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com