2-((3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(o-tolyl)acetamide CAS 476485-66-2
| CAS No. | 476485-66-2 |
| Molecular Formula | C26H25N3O3S2 |
| Molecular Weight | 491.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 491.63 g/mol gives 2-((3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(o-tolyl)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-((3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(o-tolyl)acetamide (CAS 476485-66-2) is a high-purity analytical reference standard with the molecular formula C26H25N3O3S2 and a molecular weight of 491.63 g/mol.
The molecular framework of 2-((3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(o-tolyl)acetamide (C26H25N3O3S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-((3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(o-tolyl)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H25N3O3S2 |
| Molecular Weight | 491.63 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Methoxyphenyl Standards
- 2-((3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(m-tolyl)acetamide (CAS 477330-41-9)
- 4-Methoxyphenyl 2-Azido-3,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside (CAS 1272755-25-5)
- 5-(4-Methoxyphenyl)-3-perfluorohexyl-1H-pyrazole (CAS 1029636-49-4)
- 6-(4-Methoxyphenyl)-2-((2-tosylethyl)thio)-4-(trifluoromethyl)nicotinonitrile (CAS 625376-41-2)
- 2-((5-(4-Methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N,N-diphenylacetamide (CAS 332385-00-9)
- 3-(4-Methoxyphenyl)-2-((2-(3-methoxyphenyl)-2-oxoethyl)thio)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 477329-25-2)
- 3-(4-Methoxyphenyl)-2-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 477329-41-2)
- (E)-{[1-(4-methoxyphenyl)-4-[(4-methylphenyl)sulfanyl]-2-phenyl-6,7-dihydro-1H-indol-5-yl]methylidene}(propan-2-yl)amine (CAS 477869-24-2)
Recommended Standards
- 2-((3-Ethyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(4-phenoxyphenyl)acetamide (CAS 618427-90-0)
- 2-Desisopropyl-2-phenyl Repaglinide-d5 (Repaglinide Impurity) (CAS 1346598-75-1)
- Valsartan Impurity 136 (CAS CATO-C4X-1057136)
- Ethyl (2S)-2-{4-[({5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}sulfanyl)methyl]benzenesulfonamido}-4-methylpentanoate (CAS 1031212-65-3)
- 1-(4-Aminobutyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine (CAS 313350-31-1)
- 6-Acetylacteoside (CAS 441769-43-3)
- tert-Butyl cis-6-oxo-7-oxa-5-azaspiro[3.4]octane-2-carboxylate (CAS 2135785-61-2)
- 1-(OXETAN-3-YL)PIPERAZINE HCL (CAS 1369338-92-0)
- Methotrexate Impurity 44 (CAS 93528-16-6)
- 4-[(4-benzylpiperazin-1-yl)methyl]-1,3-thiazol-2-amine (CAS 1097046-57-5)
- (R)-tert-Butyl 1-propionylpyrrolidin-3-ylcarbamate (CAS 1286208-90-9)
- DL-Folic Acid (CAS 65165-92-6)
- (7-Fluoro-1H-indol-5-yl)boronic acid (CAS 2077188-75-9)
- Tyr-Proinsulin C-Peptide (55-89) (human) (CAS 139532-11-9)
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