6-(4-Methoxyphenyl)-2-((2-tosylethyl)thio)-4-(trifluoromethyl)nicotinonitrile CAS 625376-41-2
| CAS No. | 625376-41-2 |
| Molecular Formula | C23H19F3N2O3S2 |
| Molecular Weight | 492.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
6-(4-Methoxyphenyl)-2-((2-tosylethyl)thio)-4-(trifluoromethyl)nicotinonitrile (CAS 625376-41-2), molecular formula C23H19F3N2O3S2 and molecular weight 492.53 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-(4-Methoxyphenyl)-2-((2-tosylethyl)thio)-4-(trifluoromethyl)nicotinonitrile (C23H19F3N2O3S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H19F3N2O3S2 |
| Molecular Weight | 492.53 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
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Recommended Standards
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- 5-Chloro-7-fluoro-3,4-dihydronaphthalen-1(2H)-one (CAS 1092348-26-9)
- 2-Bromo-4-(4-methylpiperazin-1-yl)pyrimidine (CAS 1209459-23-3)
- (S)-2-(3-bromo-2-fluorophenyl)pyrrolidine (CAS 1228569-31-0)
- 2-(Phenylethynyl)aniline (CAS 13141-38-3)
- Fluralaner Impurity 17 (CAS CATO-C4X-218017)
- Methyl 3-(4-bromobenzenesulfonyl)propanoate (CAS 14223-24-6)
- Methyl 2-(2-(2,4-dichlorophenoxy)acetamido)-5-((2-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 335409-01-3)
- (1-(4-Fluorophenyl)-3,5-dimethyl-1H-pyrazol-4-yl)methanamine hydrochloride (CAS 1255717-06-6)
- 3-Amino-3-(2,4,5-trimethoxyphenyl)propan-1-ol (CAS 1281938-06-4)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
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