3-((2-Chloro-6-fluorobenzyl)thio)-5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazole CAS 477331-50-3
| CAS No. | 477331-50-3 |
| Molecular Formula | C22H16Cl2FN3S |
| Molecular Weight | 444.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 444.35 g/mol gives 3-((2-Chloro-6-fluorobenzyl)thio)-5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-((2-Chloro-6-fluorobenzyl)thio)-5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazole (CAS 477331-50-3), a certified reference material (molecular formula C22H16Cl2FN3S, MW 444.35 g/mol) for analytical method development and quality control.
3-((2-Chloro-6-fluorobenzyl)thio)-5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazole (C22H16Cl2FN3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-((2-Chloro-6-fluorobenzyl)thio)-5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H16Cl2FN3S |
| Molecular Weight | 444.35 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-N-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)phenyl)nicotinamide (CAS 1024069-88-2)
- 2-({5-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]pyrimidin-2-yl}sulfanyl)-1-(4-chlorophenyl)ethan-1-one (CAS 344263-13-4)
- 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-(4-chlorophenyl)pyridine-3-carboxamide (CAS 338412-91-2)
- 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-iodo-6-nitrophenol (CAS 1400872-24-3)
- 3-Chloro-6'-(2,4-dichlorophenoxy)-5-(trifluoromethyl)-[2,3'-bipyridine]-5'-carbonitrile (CAS 339011-79-9)
- 4-Chloro-N-(4-chloro-phenyl)-N-(6-chloro-4-trifluoromethyl-pyridin-2-yl)-benzamidine (CAS 1311283-67-6)
- 3-Chloro-2-[(1E)-(2,4-dichlorophenyl)(2-phenylhydrazin-1-ylidene)methyl]-5-(trifluoromethyl)pyridine (CAS 306977-42-4)
- Methyl 2-(2-(2-chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl)hydrazinyl)-4-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 648427-12-7)
Recommended Standards
- trans-(4-{[(4-Iodophenyl)-methyl-amino]-methyl}-cyclohexyl)-carbamic acid tert-butyl ester (CAS 1313365-62-6)
- 7-[4-(4-Fluorophenyl)piperazin-1-yl]-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 477851-78-8)
- 1246815-66-6 Rhein Disulfate (CAS 1246815-66-6)
- 6-Bromo-1-(sec-butyl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-1H-indole-4-carboxamide (CAS 1346574-53-5)
- 2-Iodo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid (CAS 2138337-72-9)
- 2-Chloro-N-(2,5-dimethylphenyl)isonicotinamide (CAS 1019383-36-8)
- 1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazol-4-amine (CAS 1171662-77-3)
- 4-Methylpyridine hydrochloride (CAS 14401-93-5)
- 2-(4-((Trifluoromethyl)thio)phenyl)acetic acid (CAS 243977-23-3)
- tert-Butyl (2R)-2-formyl-2-methyl-pyrrolidine-1-carboxylate (CAS 1623409-38-0)
- 2-[1-(aminomethyl)cyclobutyl]acetic acid (CAS 748754-87-2)
- Nebivolol Impurity 44 (CAS 920275-19-0)
- 6-((Pyrrolidin-3-ylmethyl)amino)nicotinonitrile (CAS 1258826-80-0)
- Semaglutide impurity 255 (CAS CATO-C4X-2226255)
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