4-(4-Chlorobenzoyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one CAS 477332-99-3
| CAS No. | 477332-99-3 |
| Molecular Formula | C20H13ClN4O5S |
| Molecular Weight | 456.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(4-Chlorobenzoyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 477332-99-3) is a high-purity analytical reference standard with the molecular formula C20H13ClN4O5S and a molecular weight of 456.86 g/mol.
Based on its molecular formula C20H13ClN4O5S, 4-(4-Chlorobenzoyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 456.86 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 4-(4-Chlorobenzoyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H13ClN4O5S |
| Molecular Weight | 456.86 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chlorobenzoyl Standards
- [2-[[3-(2-Chlorobenzoyl)-5-ethyl-2-thienyl]amino]-2-oxoethyl]carbamic Acid Benzyl Ester (CAS 50508-73-1)
- N'-(4-chlorobenzoyl)-1-((4-chlorophenyl)sulfonyl)piperidine-4-carbohydrazide (CAS 477872-87-0)
- 5-(4-Chlorobenzoyl)-6-(3,4-dimethoxyphenyl)-4-hydroxy-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one (CAS 623936-46-9)
- 5-(4-Chlorobenzoyl)-6-(3-ethoxy-4-hydroxyphenyl)-4-hydroxy-4-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one (CAS 474005-43-1)
- 4-(4-Chlorobenzoyl)-3-methyl-1-(4-(trifluoromethyl)benzyl)-3,4-dihydroquinoxalin-2(1H)-one (CAS 317822-28-9)
- (Z)-3-(((4-chlorobenzoyl)oxy)imino)-1-(2,4-dichlorobenzyl)indolin-2-one (CAS 320419-58-7)
- 4-(4-Chlorobenzoyl)-1-(2,4-dichlorobenzyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 317822-45-0)
- 4-(4-Chlorobenzoyl)-1-(2,6-dichlorobenzyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 317822-30-3)
Recommended Standards
- 6-(((4-Chlorophenyl)thio)methyl)-2-((3,4-dichlorobenzyl)thio)-N-methylpyrimidin-4-amine (CAS 478261-62-0)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-N-(3-methoxybenzyl)-1-methyl-1H-imidazole-5-carboxamide (CAS 339278-17-0)
- 5-Bromo-4-chloro-3-indolyl myristate (CAS 341972-95-0)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-5-[(E)-2-[(4-fluorophenyl)amino]ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338413-05-1)
- Methyl 2-(4-fluorophenyl)-5-phenyloxazole-4-carboxylate (CAS 1427954-46-8)
- (S)-1-Benzyl-2-(bromomethyl)pyrrolidine (CAS 1353996-05-0)
- 3-(Tributylstannyl)benzoic acid (CAS 273747-03-8)
- 2-[(4-Oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy]propanoic acid (CAS 374702-07-5)
- N-(Pyridin-3-ylmethyl)ethanamine (CAS 3000-75-7)
- Tafamidis (CAS 594839-88-0)
- 4-Bromo-2,5-difluoro-N,N-dimethylbenzamide (CAS 1449008-10-9)
- ethyl 5-benzyloxy-4-oxo-pyran-3-carboxylate (CAS 1246743-88-3)
- 6-Benzyltetrahydro-2H-pyran-2-one (CAS 40564-46-3)
- Palmitoyl Tripeptide-5 TFA (CAS 623172-55-4（free base）)
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