2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-N-(3-methoxybenzyl)-1-methyl-1H-imidazole-5-carboxamide CAS 339278-17-0
| CAS No. | 339278-17-0 |
| Molecular Formula | C19H16ClF3N4O2S |
| Molecular Weight | 456.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-N-(3-methoxybenzyl)-1-methyl-1H-imidazole-5-carboxamide (C19H16ClF3N4O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-N-(3-methoxybenzyl)-1-methyl-1H-imidazole-5-carboxamide (CAS 339278-17-0), molecular formula C19H16ClF3N4O2S and molecular weight 456.87 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-N-(3-methoxybenzyl)-1-methyl-1H-imidazole-5-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H16ClF3N4O2S |
| Molecular Weight | 456.87 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-5-[(E)-2-[(4-fluorophenyl)amino]ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338413-05-1)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)-N-(3,5-dimethylphenyl)benzenesulfonamide (CAS 338775-29-4)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}-N-(2,3-dimethylphenyl)benzene-1-sulfonamide (CAS 338775-36-3)
- 2-Chloro-N'-(2-(4-methoxyphenyl)imidazo[1,2-a]pyridine-6-carbonyl)benzenesulfonohydrazide (CAS 866137-85-1)
- 3-(3-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-1-tosyl-1H-pyrazole (CAS 477712-64-4)
- 3-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-1-(4-methylbenzenesulfonyl)-1H-pyrazole (CAS 477710-94-4)
- 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(phenylcarbamoyl)amino]-4,5-dihydro-1,2-oxazole-3-carboxamide (CAS 338399-32-9)
- 4-Chloro-2-(4-(N,N-diethylsulfamoyl)phenyl)quinoline-6-sulfonyl fluoride (CAS 31242-12-3)
Recommended Standards
- 4-(4-Chlorobenzoyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 477332-99-3)
- 6-(((4-Chlorophenyl)thio)methyl)-2-((3,4-dichlorobenzyl)thio)-N-methylpyrimidin-4-amine (CAS 478261-62-0)
- 5-Bromo-4-chloro-3-indolyl myristate (CAS 341972-95-0)
- N1,N2-didodecylethanebis(thioamide) (CAS 120-88-7)
- 4-(5-Methyl-3-nitro-1H-pyrazol-1-yl)butanoic acid (CAS 696646-55-6)
- 2-(3-azidoazetidin-1-yl)-N-phenylacetamide (CAS 2098077-11-1)
- methyl 2-fluoro-4-(5-methyl-1H-1,2,3,4-tetrazol-1-yl)benzoate (CAS 1864015-28-0)
- 2-(3-Methoxyphenyl)-5-(1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl)-1,3,4-oxadiazole (CAS 338747-63-0)
- (S)-1-(4-Bromo-3-fluorophenyl)pent-4-en-1-amine (CAS 2166260-33-7)
- 2-Bromo-4-(5-hydroxy-3-methyl-1H-pyrazol-1-yl)benzonitrile (CAS 1008520-71-5)
- Palbociclib Impurity 78 (CAS 153473-24-6)
- (S)-2-(4-Fluorophenyl)piperazine (CAS 612507-29-6)
- dimethyl 5-(3-aminophenyl)-2,3-dihydro-1H-pyrrolizine-6,7-dicarboxylate (CAS 1110927-76-8)
- Semaglutide impurity 203 (CAS CATO-C4X-2226203)
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