Indomethacin-D4 CAS 87377-08-0
| CAS No. | 87377-08-0 |
| Molecular Formula | - |
| Molecular Weight | 361.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Indomethacin-D4 (CAS 87377-08-0), a certified reference material (molecular formula C19H12D4ClNO4, MW 361.81 g/mol) for analytical method development and quality control.
The molecular framework of Indomethacin-D4 (C19H12D4ClNO4) is characterized by deuterium isotope labeling, a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Indomethacin-D4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H12D4ClNO4 |
| Molecular Weight | 361.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Indomethacin Standards
- Indomethacin Impurity 1 (CAS 4584-39-8)
- Indomethacin Isopropyl Ester (CAS 72616-25-2)
- Indomethacin heptyl ester, >98% (CAS 282728-47-6)
- Indomethacin 4-methoxyphenyl ester, 98% (CAS 261766-24-9)
- Indomethacin Impurity 2 (CAS 97460-20-3)
- Indomethacin acyl-β-D-glucuronide (CAS 75523-11-4)
- Indomethacin Impurity 24 (CAS 828-94-4)
- NO-Indomethacin (CAS 301838-28-8)
Recommended Standards
- 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-4-[3-(trifluoromethyl)phenyl]piperazine (CAS 477848-01-4)
- Ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-methylacetamido)acetate (CAS 1035404-17-1)
- 1-(5-Chloro-2-methylphenyl)-5-((pyrimidin-2-ylthio)methyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1416346-35-4)
- ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-methylacetamido)acetate (CAS 1035404-19-3)
- 5-((3-Aminopropyl)amino)thieno[3,2-b]pyridin-7(4H)-one dihydrochloride (CAS 1016552-68-3)
- 4-Amino-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide (CAS 1211025-52-3)
- 4-Chloro-6-(1-ethyl-3-methyl-1H-pyrazol-5-yl)-2-(1-methoxyethyl)pyrimidine (CAS 1708437-44-8)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-propylthiazol-4-yl)boronate (CAS 2223039-22-1)
- 1-Allyl-2-(2-chloropyridin-3-yl)-1H-benzo[d]imidazole (CAS 400081-26-7)
- 849015-95-8 2-(3-formylphenoxy)acetamide DTXSID20454607 (CAS 849015-95-8)
- 2-(Boc-amino)-5-methoxy-5-oxopentanoic Acid (CAS 112159-16-7)
- 2-(6-Amino-[3,3'-bipyridin]-4-yl)acetic acid (CAS 1227572-31-7)
- 4-chloro-3,8-dimethylquinoline (CAS 39593-12-9)
- Des-Gly29,30-Tirzepatide (CAS CATO-CPTD788944)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com