N-(4-chlorophenyl)-N-methyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-4-carboxamide CAS 477850-92-3
| CAS No. | 477850-92-3 |
| Molecular Formula | C23H17ClN2O2 |
| Molecular Weight | 388.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 388.85 g/mol gives N-(4-chlorophenyl)-N-methyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-4-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(4-chlorophenyl)-N-methyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-4-carboxamide (CAS 477850-92-3) is a high-purity analytical reference standard with the molecular formula C23H17ClN2O2 and a molecular weight of 388.85 g/mol.
Structurally, N-(4-chlorophenyl)-N-methyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-4-carboxamide (C23H17ClN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 388.85 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-chlorophenyl)-N-methyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H17ClN2O2 |
| Molecular Weight | 388.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- (2Z)-2-[(4-Chlorophenyl)imino]-N-(4-methylphenyl)-2H-chromene-3-carboxamide (CAS 1261027-74-0)
- Benzyl (2-(4-chlorophenyl)quinolin-4-yl)carbamate (CAS 861208-67-5)
- N-(4-Chlorophenyl)-2-(3,5-diphenyl-1H-1,2,4-triazol-1-yl)acetamide (CAS 332156-11-3)
- (3E)-1-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-3-{[(2-fluorophenyl)methoxy]imino}propan-1-one (CAS 339279-42-4)
- (E)-{1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene}amino 4-fluorobenzoate (CAS 477872-46-1)
- 4-[(2E)-3-(3-Chlorophenyl)prop-2-enoyl]phenyl (2E)-3-phenylprop-2-enoate (CAS 298216-12-3)
- Methyl 2-(5-(4-chlorophenyl)-7-methoxy-2-thioxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)acetate (CAS 1260530-39-9)
- 2-((5-(((4-Chlorophenyl)amino)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide (CAS 1306739-85-4)
Recommended Standards
- Vardenafil Impurity 50 (CAS CATO-C4X-101750)
- N-(3-Benzyl-2-quinoxalinyl)-3-chlorobenzenecarbohydrazide (CAS 478033-89-5)
- Sildenafil Impurity 5 (CAS 1058653-74-9)
- Sulfadiazine Impurity 18 (CAS 345936-70-1)
- Tert-butyl ((1S,2R)-2-amino-4,4-difluorocyclopentyl)carbamate (CAS 1638744-07-6)
- tert-Butyl 2-(6-methoxypyridin-3-yl)pyrrolidine-1-carboxylate (CAS 1352534-79-2)
- 2-[(3AR)-1-benzoyl-3a-methyl-5-oxo-octahydropyrrolo[2,3-b]pyrrol-2-yl]phenyl benzoate (CAS 956731-14-9)
- 2-[(2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]-N-{[(4-nitrophenyl)carbamothioyl]amino}acetamide (CAS 1024193-20-1)
- 5-Fluoro-2-(3-methoxypropoxy)aniline (CAS 946729-34-6)
- H-D-Phe-pNA (CAS 14235-18-8)
- (R)-N-Ethylidene-2-methylpropane-2-sulfinamide (CAS 439117-21-2)
- N,N-Dimethyl-N'-(4-methylbenzyl)-1,2-ethanediamine dihydrochloride (CAS 1158367-04-4)
- 1-(5-Methylthiophen-2-yl)-2-(pyrrolidin-2-yl)ethan-1-one (CAS 1520784-11-5)
- Semaglutide impurity 108 (CAS CATO-C4X-2226108)
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