Vardenafil Impurity 50 CAS CATO-C4X-101750
| CAS No. | CATO-C4X-101750 |
| Molecular Formula | C19H21ClN4O3 |
| Molecular Weight | 388.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Vardenafil Impurity 50 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Vardenafil Impurity 50 (CAS CATO-C4X-101750), a pharmacopoeial impurity reference standard (molecular formula C19H21ClN4O3, MW 388.85 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C19H21ClN4O3, Vardenafil Impurity 50 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 388.85 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H21ClN4O3 |
| Molecular Weight | 388.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Vardenafil Standards
- Vardenafil Impurity 67 (CAS 448184-60-9)
- Vardenafil EP Impurity B (CAS 437717-43-6)
- Vardenafil Impurity 60 (CAS CATO-C4X-101760)
- Vardenafil Impurity 39 (CAS 2580939-41-7)
- Vardenafil Impurity 15 (CAS CATO-C4X-101715)
- Vardenafil Impurity 53 (CAS CATO-C4X-101753)
- Vardenafil Impurity 24 (CAS 910554-77-7)
- Vardenafil Impurity 55 (CAS 2520113-41-9)
Recommended Standards
- N-(4-chlorophenyl)-N-methyl-1-oxo-2-phenyl-1,2-dihydroisoquinoline-4-carboxamide (CAS 477850-92-3)
- Sildenafil Impurity 5 (CAS 1058653-74-9)
- N-(4-Chlorophenyl)-2-(3,5-diphenyl-1H-1,2,4-triazol-1-yl)acetamide (CAS 332156-11-3)
- Sulfadiazine Impurity 18 (CAS 345936-70-1)
- Luliconazole impurity 24 (CAS 1579886-24-0)
- Amlodipine Impurity 60 (CAS 949155-13-9)
- Salbutamol EP Impurity J(HCl) (CAS 41489-89-8)
- 1,3,5-Tris(formylphenoxymethyl)benzene (CAS 437981-33-4)
- Ethyl 2-bromo-6-chloroisonicotinate (CAS 1214388-02-9)
- 1-(2-Chlorophenyl)-2-Thiourea (CAS 5344-82-1)
- Ethyl 5-bromo-2,4-difluorobenzoate (CAS 1260677-99-3)
- Prop-2-yn-1-yl benzenesulfonate (CAS 6165-75-9)
- Metformin Hydrochloride (CAS 1115-70-4)
- Des-[Oct-γ-Glu-AEEA-AEEA]-Semaglutide (CAS CATO-C4X-2226112)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com