3-(Chlorodifluoromethyl)-6-(pyridin-2-ylthio)-[1,2,4]triazolo[4,3-b]pyridazine CAS 477871-73-1
| CAS No. | 477871-73-1 |
| Molecular Formula | C11H6ClF2N5S |
| Molecular Weight | 313.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 313.71 g/mol gives 3-(Chlorodifluoromethyl)-6-(pyridin-2-ylthio)-[1,2,4]triazolo[4,3-b]pyridazine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(Chlorodifluoromethyl)-6-(pyridin-2-ylthio)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 477871-73-1), molecular formula C11H6ClF2N5S and molecular weight 313.71 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(Chlorodifluoromethyl)-6-(pyridin-2-ylthio)-[1,2,4]triazolo[4,3-b]pyridazine (C11H6ClF2N5S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(Chlorodifluoromethyl)-6-(pyridin-2-ylthio)-[1,2,4]triazolo[4,3-b]pyridazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H6ClF2N5S |
| Molecular Weight | 313.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Chlorodifluoromethyl Standards
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- 2-(Chlorodifluoromethyl)-4,6-bis(trifluoromethyl)-1,3,5-triazine (CAS 328-77-8)
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Recommended Standards
- 3-((4-Chlorophenyl)sulfonyl)-5-nitrophenol (CAS 862649-86-3)
- 4-(4-Nitrophenoxy)benzenesulfonyl chloride (CAS 61404-92-0)
- 2-(2-Chloro-4-fluoro-5-(5-hydroxy-1-methyl-1H-pyrazol-3-yl)phenoxy)-N-methylacetamide (CAS 2151826-99-0)
- 6-Amino-4-(3-chloro-4-fluorophenoxy)quinoline-3-carbonitrile (CAS 928779-56-0)
- Calcium 9-ethyl-4,6-dioxo-10-propyl-6,9-dihydro-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylate (CAS 101626-68-0)
- Azothoate (CAS 5834-96-8)
- 5-Chloro-2-(2-methoxy-4-methylphenoxy)aniline (CAS 937606-35-4)
- Cytarabine Impurity 8 (CAS 58461-29-3)
- Dimethyl 5-methyl-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate (CAS 75475-91-1)
- 2-Formyl-6-(trifluoromethyl)benzoic acid (CAS 1289156-92-8)
- 3-(3-Chlorophenyl)piperidine (CAS 55989-12-3)
- 5-(4-Chlorophenoxy)-1-methyl-4-nitro-1H-imidazole (CAS 95862-50-3)
- 2-(Adamantan-1-ylformamido)-3-phenylpropanoic acid (CAS 1397003-14-3)
- Semaglutide impurity 40 (CAS CATO-C4X-222640)
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