6-Chloro-2-(4-chlorophenyl)-3-[(4-chlorophenyl)sulfanyl]quinoline-4-carboxylic acid CAS 477886-51-4
| CAS No. | 477886-51-4 |
| Molecular Formula | C22H12Cl3NO2S |
| Molecular Weight | 460.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 460.76 g/mol gives 6-Chloro-2-(4-chlorophenyl)-3-[(4-chlorophenyl)sulfanyl]quinoline-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Chloro-2-(4-chlorophenyl)-3-[(4-chlorophenyl)sulfanyl]quinoline-4-carboxylic acid (CAS 477886-51-4), molecular formula C22H12Cl3NO2S and molecular weight 460.76 g/mol, is a CATO reference standard with documented purity and traceability.
6-Chloro-2-(4-chlorophenyl)-3-[(4-chlorophenyl)sulfanyl]quinoline-4-carboxylic acid (C22H12Cl3NO2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Chloro-2-(4-chlorophenyl)-3-[(4-chlorophenyl)sulfanyl]quinoline-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H12Cl3NO2S |
| Molecular Weight | 460.76 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
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- 6-Ethyl-5-(4-fluoro-3-nitrophenyl)pyrimidine-2,4-diamine (CAS 113494-35-2)
- 2-(5-(Pyridin-4-yl)-1,3,4-oxadiazol-2-yl)aniline (CAS 54754-58-4)
- 4-Methyl-3-((pyridin-4-ylmethyl)amino)benzoic acid (CAS 878714-36-4)
- 4-Bromo-1<I>H</I>-indazole (CAS 186407-74-9)
- 4-(2-Methylbutan-2-yl)aniline (CAS 2049-92-5)
- D-Ile12-Tirzepatide (CAS CATO-CPTD788921)
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