N-(6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)-3-(trifluoromethyl)benzamide CAS 477869-97-9
| CAS No. | 477869-97-9 |
| Molecular Formula | C19H11ClF6N4O |
| Molecular Weight | 460.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 460.76 g/mol gives N-(6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)-3-(trifluoromethyl)benzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies N-(6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)-3-(trifluoromethyl)benzamide (CAS 477869-97-9), a certified reference material (molecular formula C19H11ClF6N4O, MW 460.76 g/mol) for analytical method development and quality control.
The molecular framework of N-(6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)-3-(trifluoromethyl)benzamide (C19H11ClF6N4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H11ClF6N4O |
| Molecular Weight | 460.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related N Standards
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Recommended Standards
- (Z)-{[2-(4-chlorophenyl)cyclopropyl](4-methoxyphenyl)methylidene}[(2,4-dichlorophenyl)methoxy]amine (CAS 338962-87-1)
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- 5-Pentacosylbenzene-1,3-diol (CAS 70110-61-1)
- N<SUB>(im)</SUB>-trityl-<SC>L</SC>-histidine-propionamide (CAS 171176-63-9)
- 6-Chloro-2-(4-fluorophenyl)-4H-chromen-4-one (CAS 213894-75-8)
- 1803713-15-6 2,4-Dibromo-6-(difluoromethoxy)phenylacetic acid (CAS 1803713-15-6)
- 6-Chloro-5-hydroxypicolinaldehyde (CAS 1211538-40-7)
- Nicotinamide EP Impurity E (CAS 1986-81-8)
- (3-Ethyl-1,2,4-thiadiazol-5-yl)boronic acid (CAS 213325-86-1)
- 3-Amino-1-(2-hydroxyethyl)-4-phenyl-1,4,5,7-tetrahydro-6h-pyrazolo[3,4-b]pyridin-6-one (CAS 1395786-34-1)
- Chelidamic Acid Monohydrate (CAS 199926-39-1)
- N1-(2-(Methylthio)phenyl)-N2-((1-(thiophen-2-yl)cyclopentyl)methyl)oxalamide (CAS 1058475-56-1)
- 4-Chloro-3-(thiophene-2-amido)benzoic acid (CAS 379254-57-6)
- Insulin Degludec Impurity 24 (CAS CATO-C4X-215724)
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