(2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-1-[4-(2-fluorophenyl)piperazin-1-yl]prop-2-en-1-one CAS 477888-67-8
| CAS No. | 477888-67-8 |
| Molecular Formula | C26H23Cl2FN2O2 |
| Molecular Weight | 485.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-1-[4-(2-fluorophenyl)piperazin-1-yl]prop-2-en-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 485.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies (2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-1-[4-(2-fluorophenyl)piperazin-1-yl]prop-2-en-1-one (CAS 477888-67-8), a certified reference material (molecular formula C26H23Cl2FN2O2, MW 485.38 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-1-[4-(2-fluorophenyl)piperazin-1-yl]prop-2-en-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H23Cl2FN2O2 |
| Molecular Weight | 485.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- 2-[(2,6-Dichlorophenyl)methanesulfonyl]-4,5-diphenyl-1-propyl-1H-imidazole (CAS 339277-32-6)
- 5-[(2,6-Dichlorophenyl)sulfanyl]-4-{[(4-methoxyphenyl)methoxy]methyl}-1-methyl-3-phenyl-1H-pyrazole (CAS 318248-44-1)
- (5-((3,5-Dichlorophenyl)thio)-1-dodecyl-4-isopropyl-1H-imidazol-2-yl)methanol (CAS 178979-07-2)
- Methyl 4-{[(5-{[(2,6-dichlorophenyl)methanesulfinyl]methyl}-4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}benzoate (CAS 344271-91-6)
- 1023504-62-2 3-(2,3-Dichlorophenyl)-1-(4-((6,7-dimethoxy(3,4-dihydroisoquinolyl))methyl)phenyl)urea MFCD03839403 (CAS 1023504-62-2)
- 1024375-31-2 3-(3,4-Dichlorophenyl)-1-(4-((6,7-dimethoxy(3,4-dihydroisoquinolyl))methyl)phenyl)urea MFCD03839406 (CAS 1024375-31-2)
- (3-(2,6-Dichlorophenyl)-5-methylisoxazol-4-yl)(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methanone (CAS 378753-06-1)
- (4E)-4-{[(3,5-dichlorophenyl)amino]methylidene}-1-[4-(trifluoromethoxy)phenyl]-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 338403-28-4)
Recommended Standards
- 7-(4-Bromophenyl)-2-(4-(2-fluorophenyl)piperazin-1-yl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1242861-55-7)
- 1-(2,6-Dichlorobenzyl)-3'-(4-methoxyphenyl)spiro[indoline-3,2'-thiazolidine]-2,4'-dione (CAS 400081-78-9)
- 3-Ethyl 5-methyl 2-{[2-(2-chloroacetamido)ethoxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate (CAS 743452-10-0)
- 2-(Naphthalen-2-yl)-4-phenyl-6-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1,3,5-triazine (CAS 2741917-59-7)
- (7-Methoxycoumarin-4-yl)acetic acid (CAS 62935-72-2)
- Tert-butyl 4-isobutoxypiperidine-1-carboxylate (CAS 509147-80-2)
- 4-(Trifluoromethoxy)benzene-1,3-diol (CAS 1395038-04-6)
- 3-(O-tolyl)-3-(2,2,2-trifluoroacetamido)propanoic acid (CAS 117291-10-8)
- 1,2-Di-p-tolylethylenediamine (CAS 124842-96-2)
- N-Methyl-2-(morpholinomethyl)aniline (CAS 937659-58-0)
- 6-Methoxybenzo[d][1,3]dioxole-4-carboxylic acid (CAS 401811-79-8)
- 7H-Benzo[de]benzo[4,5]imidazo[2,1-a]isoquinolin-7-one (CAS 23749-58-8)
- 6-Methyl-2-(methylthio)-5-(piperidin-1-ylmethyl)pyrimidin-4-ol (CAS 343218-96-2)
- Tirzepatide Impurity 19 X TFA Salt (CAS CATO-C4X-324019)
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