(2E)-3-{4-[(4-bromophenyl)methoxy]phenyl}-N-[(thiophen-2-yl)methyl]prop-2-enamide CAS 477889-37-5
| CAS No. | 477889-37-5 |
| Molecular Formula | C21H18BrNO2S |
| Molecular Weight | 428.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 428.34 g/mol gives (2E)-3-{4-[(4-bromophenyl)methoxy]phenyl}-N-[(thiophen-2-yl)methyl]prop-2-enamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(2E)-3-{4-[(4-bromophenyl)methoxy]phenyl}-N-[(thiophen-2-yl)methyl]prop-2-enamide (CAS 477889-37-5) is a high-purity analytical reference standard with the molecular formula C21H18BrNO2S and a molecular weight of 428.34 g/mol.
(2E)-3-{4-[(4-bromophenyl)methoxy]phenyl}-N-[(thiophen-2-yl)methyl]prop-2-enamide (C21H18BrNO2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2E)-3-{4-[(4-bromophenyl)methoxy]phenyl}-N-[(thiophen-2-yl)methyl]prop-2-enamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H18BrNO2S |
| Molecular Weight | 428.34 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((3-methylbut-2-en-1-yl)amino)-2-(methylselanyl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol (CAS 110085-70-6)
- 2-[Difluoro-(3,4,5-trifluorophenoxy)methyl]-1,3-difluoro-5-(4-propylphenyl)benzene (CAS 303186-20-1)
- 7-(4-(Pyrimidin-2-yl)piperazin-1-yl)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 477851-79-9)
- Vismodegib-d7 (CAS 2733145-73-6)
- 84282-26-8 (Isodecanoato-O)(neodecanoato-O)zinc EINECS 282-673-2 (CAS 84282-26-8)
- 3,5-Pyridinedicarbonyl dichloride (CAS 15074-61-0)
- 7-Iodonaphthalen-2-ol (CAS 128542-51-8)
- 1-(tert-Butyl) 2-methyl (2S,4S)-4-bromopyrrolidine-1,2-dicarboxylate (CAS 334999-29-0)
- (S)-2-Amino-N-(4-((cyclopropylmethyl)amino)cyclohexyl)-3-methylbutanamide (CAS 1354010-57-3)
- 6-Fluorohexan-1-ol (CAS 373-32-0)
- 3-(3,4-difluorophenyl)prop-2-enenitrile (CAS 1226484-97-4)
- (2s)-2-(4-Acetylbenzenesulfonamido)propanoic acid (CAS 1212335-61-9)
- (2-Hydroxybenzyl)triphenylphosphonium bromide (CAS 70340-04-4)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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