4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 2-chlorobenzoate CAS 477889-71-7
| CAS No. | 477889-71-7 |
| Molecular Formula | C25H20ClNO5 |
| Molecular Weight | 449.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 2-chlorobenzoate (C25H20ClNO5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 2-chlorobenzoate (CAS 477889-71-7), molecular formula C25H20ClNO5 and molecular weight 449.88 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 2-chlorobenzoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H20ClNO5 |
| Molecular Weight | 449.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methoxy Standards
- 4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 4-chlorobenzoate (CAS 477890-05-4)
- 4-Methoxy-N-{2,5,6-trimethyl-1-[(3-methylphenyl)methyl]-1H-1,3-benzodiazol-4-yl}benzene-1-sulfonamide (CAS 338964-16-2)
- Ethyl 6-(2-methoxy-2-oxoethyl)-4-((4-methoxyphenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylate (CAS 866134-49-8)
- N-(4-methoxy-2-nitrophenyl)-N-(phenylsulfonyl)benzenesulfonamide (CAS 159383-46-7)
- 1-Methoxy-9H-fluorene (CAS 26060-14-0)
- N1-[4-methoxy-2-(trifluoromethyl)phenyl]-2-[3-chloro-3-(4-chlorophenyl)prop-2-enylidene]hydrazine-1-carbothioamide (CAS 680212-21-9)
- 4-Methoxy-N-(1-(4-methoxybenzyl)-5,6-dimethyl-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338954-91-9)
- 4-Methoxy-N-{1-[(3-methoxyphenyl)methyl]-5,6-dimethyl-1H-1,3-benzodiazol-4-yl}benzene-1-sulfonamide (CAS 338955-15-0)
Recommended Standards
- 4-(4-(Allyloxy)benzoyl)-5-(4-chlorophenyl)-1-(furan-2-ylmethyl)-3-hydroxy-1H-pyrrol-2(5H)-one (CAS 618077-28-4)
- N-{2-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]pyridin-3-yl}-4-methylbenzamide (CAS 338772-61-5)
- MK8722 (CAS 1394371-71-1)
- 5-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 400075-72-1)
- 2-Chloro-5-(4-methylpiperidine-1-carbonyl)pyridine (CAS 385407-85-2)
- 7789-45-9 1KC430K0ZN Copper(II) bromide Cupric bromide Copper bromide (CuBr2) Copper dibromide EINECS 232-167-2 HSDB 257 UNII-1KC430K0ZN (CAS 7789-45-9)
- 1-Ethynylcyclopropane-1-sulfinate (sodium) (CAS 2917638-88-9)
- methyl 3-aminothietane-3-carboxylate (CAS 1001426-63-6)
- 2-Methylpropyl-2-d1 Alcohol (CAS 20440-13-5)
- 4-Amino-6-(5-methoxy-1H-indol-3-yl)-1,6-dihydro-1,3,5-triazine-2-thiol (CAS 1142208-41-0)
- (2R,3S)-5-acetoxy-2-(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-methylbenzoate (CAS 40491-01-8)
- 2-(3-Chloro-5-nitropyridin-2-yl)acetic acid (CAS 1694868-90-0)
- Rel-(3R,4S,5S)-5-((R)-1,2-dihydroxyethyl)-3,4-dihydroxydihydrofuran-2(3H)-one (CAS 3327-64-8)
- Acetyl Hexapeptide-38 (CAS 1400634-44-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com