4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 4-chlorobenzoate CAS 477890-05-4
| CAS No. | 477890-05-4 |
| Molecular Formula | C25H20ClNO5 |
| Molecular Weight | 449.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 4-chlorobenzoate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 4-chlorobenzoate (CAS 477890-05-4) is a high-purity analytical reference standard with the molecular formula C25H20ClNO5 and a molecular weight of 449.88 g/mol.
4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 4-chlorobenzoate (C25H20ClNO5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 4-chlorobenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H20ClNO5 |
| Molecular Weight | 449.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methoxy Standards
- 4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 2-chlorobenzoate (CAS 477889-71-7)
- 4-Methoxy-N-{2,5,6-trimethyl-1-[(3-methylphenyl)methyl]-1H-1,3-benzodiazol-4-yl}benzene-1-sulfonamide (CAS 338964-16-2)
- Ethyl 6-(2-methoxy-2-oxoethyl)-4-((4-methoxyphenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylate (CAS 866134-49-8)
- N-(4-methoxy-2-nitrophenyl)-N-(phenylsulfonyl)benzenesulfonamide (CAS 159383-46-7)
- 1-Methoxy-9H-fluorene (CAS 26060-14-0)
- N1-[4-methoxy-2-(trifluoromethyl)phenyl]-2-[3-chloro-3-(4-chlorophenyl)prop-2-enylidene]hydrazine-1-carbothioamide (CAS 680212-21-9)
- 4-Methoxy-N-(1-(4-methoxybenzyl)-5,6-dimethyl-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338954-91-9)
- 4-Methoxy-N-{1-[(3-methoxyphenyl)methyl]-5,6-dimethyl-1H-1,3-benzodiazol-4-yl}benzene-1-sulfonamide (CAS 338955-15-0)
Recommended Standards
- MK8722 (CAS 1394371-71-1)
- 4-(4-(Allyloxy)benzoyl)-5-(4-chlorophenyl)-1-(furan-2-ylmethyl)-3-hydroxy-1H-pyrrol-2(5H)-one (CAS 618077-28-4)
- 2-(3-Bromoadamantan-1-yl)-N-(2-((2,6-dichlorophenyl)amino)-2-oxoethyl)-N-methylacetamide (CAS 956910-01-3)
- N-{2-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]pyridin-3-yl}-4-methylbenzamide (CAS 338772-61-5)
- 1-(Benzyloxy)-2-methylpropan-2-amine (CAS 114377-40-1)
- 5-Amino-2-fluoropyridine (CAS 1827-27-6)
- bis(2-methylphenyl)methanamine (CAS 246853-44-1)
- (R)-(2,2-dichlorocyclopropyl)methanol (CAS 316377-56-7)
- N-(4-methoxyphenyl)-1-(1-methyl-2-morpholino-1H-indol-3-yl)methanimine (CAS 861212-47-7)
- 3-[4-(2-hydroxyethyl)piperazin-1-yl]-1-(10h-phenothiazin-10-yl)propan-1-one dihydrochloride 30379-54-5 AR-1F1023 (CAS 30379-54-5)
- 2-Amino-5-oxo-5-(phenylamino)pentanoic acid (CAS 4337-38-6)
- Epinastine Impurity 15 (CAS CATO-C4X-184015)
- 4-(6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)benzonitrile (CAS 662113-04-4)
- Tau Peptide (401-411)-Lys-Lys trifluoroacetate salt (CAS 2022956-59-6)
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