2-(3-Chlorobenzyl)-6-phenyl-5-(piperidin-1-yl)pyridazin-3(2H)-one CAS 478029-33-3
| CAS No. | 478029-33-3 |
| Molecular Formula | C22H22ClN3O |
| Molecular Weight | 379.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(3-Chlorobenzyl)-6-phenyl-5-(piperidin-1-yl)pyridazin-3(2H)-one (CAS 478029-33-3) is a high-purity analytical reference standard with the molecular formula C22H22ClN3O and a molecular weight of 379.88 g/mol.
The molecular framework of 2-(3-Chlorobenzyl)-6-phenyl-5-(piperidin-1-yl)pyridazin-3(2H)-one (C22H22ClN3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H22ClN3O |
| Molecular Weight | 379.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorobenzyl Standards
- 2-(2-Chlorobenzyl)-6-phenyl-5-(piperidin-1-yl)pyridazin-3(2H)-one (CAS 478029-34-4)
- Ethyl 3-((3-chlorobenzyl)oxy)pyrido[1,2-a]indole-10-carboxylate (CAS 672951-93-8)
- 1-((3-Chlorobenzyl)oxy)-6-nitro-2-phenyl-1H-benzo[d]imidazole (CAS 282523-58-4)
- 2-((2-Chlorobenzyl)sulfonyl)-1-nitro-4-(trifluoromethyl)benzene (CAS 866132-61-8)
- N-(4-chlorobenzyl)-2,2-difluoro-2-(3-(trifluoromethyl)phenoxy)acetamide (CAS 338792-67-9)
- (E)-1-(4-chlorobenzyl)-2-(2-chlorostyryl)-1H-benzo[d]imidazole (CAS 338772-25-1)
- 2-((4-Chlorobenzyl)thio)-5-(4-pentylcyclohexyl)-1,3,4-oxadiazole (CAS 860610-79-3)
- N-(2-(4-Chlorobenzyl)benzo[d]oxazol-5-yl)-4-fluorobenzamide (CAS 785836-70-6)
Recommended Standards
- 2-[(4-Chlorophenyl)methyl]-6-phenyl-5-(piperidin-1-yl)-2,3-dihydropyridazin-3-one (CAS 478029-30-0)
- 1-(6-Chloropyridazin-3-yl)-N-((hexahydro-2H-isoxazolo[2,3-a]pyridin-2-yl)methyl)piperidine-4-carboxamide (CAS 338965-04-1)
- 3-(5-(2-Chlorophenyl)furan-2-yl)-N-(2,6-diethylphenyl)acrylamide (CAS 853348-48-8)
- (E)-2-[5-(4-Chlorophenyl)-2-furyl]-N-(2-thienylmethyl)-1-ethenesulfonamide (CAS 339018-47-2)
- ((4S,4'S)-Pyridine-2,6-diylbis(4,5-dihydrooxazole-2,4-diyl))bis(methylene) diacetate (CAS 2473589-12-5)
- Ethyl 8-chloro-2-(ethylthio)-4-hydroxyquinoline-3-carboxylate (CAS 861397-35-5)
- (2R,3S)-2,3,4-trihydroxybutanoic acid & (2S,3R)-2,3,4-trihydroxybutanoic acid (CAS 10191-35-2（rac）)
- (S)-4-Benzylmorpholine-2-methanamine (CAS 186293-55-0)
- 4-iodo-1,5-dimethyl-pyrazole-3-sulfonamide (CAS 2250242-05-6)
- 5-Fluoroindole-3-acetic hydrazide (CAS 376646-57-0)
- 1-(3-Phenylpropyl)-1H-pyrrole-3-carboxylic acid (CAS 1521349-85-8)
- Methyl 2-azabicyclo[2.2.1]heptane-7-carboxylate (CAS 1559157-90-2)
- 1-(6-Hydroxy-3-methoxy-2,4-dimethylphenyl)-7-methoxynaphthalen-2-ol (CAS 1832513-67-3)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
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