2-Phenyl-5-(trifluoromethyl)-6-[4-(trifluoromethyl)benzoyl]-2,3-dihydropyridazin-3-one CAS 478043-64-0
| CAS No. | 478043-64-0 |
| Molecular Formula | C19H10F6N2O2 |
| Molecular Weight | 412.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-Phenyl-5-(trifluoromethyl)-6-[4-(trifluoromethyl)benzoyl]-2,3-dihydropyridazin-3-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-Phenyl-5-(trifluoromethyl)-6-[4-(trifluoromethyl)benzoyl]-2,3-dihydropyridazin-3-one (CAS 478043-64-0), molecular formula C19H10F6N2O2 and molecular weight 412.29 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-Phenyl-5-(trifluoromethyl)-6-[4-(trifluoromethyl)benzoyl]-2,3-dihydropyridazin-3-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 412.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C19H10F6N2O2 |
| Molecular Weight | 412.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 2-(4-Bromophenyl)-1-(4-fluorophenyl)-6,6-dimethyl-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 96757-24-3)
- 9-(4-Methoxyphenyl)-2,4-bis(trifluoromethyl)-[1,2,4]triazolo[4,3-a][1,8]naphthyridine (CAS 343372-39-4)
- 2-(2,4-Dichlorophenoxy)-N-{[(phenylformamido)methanethioyl]amino}propanamide (CAS 648860-66-6)
- N-[2-(Pyridin-3-yl)pyrimidin-4-yl]-3,5-bis(trifluoromethyl)benzamide (CAS 866143-29-5)
- Methyl 3-amino-3-(2,6-dichlorophenyl)propanoate (CAS 1038338-84-9)
- 6-Methylspiro[benzo[e][1,3]oxazine-2,4'-piperidin]-4(3H)-one hydrochloride (CAS 1451154-33-8)
- 3-(Dimethylamino)-2-isopropylphenol (CAS 1243362-76-6)
- 3-(3-Isopropylphenyl)-N-methylimidazo[1,2-a]pyrazin-8-amine (CAS 787590-84-5)
- 2-Chloro-1-[4-(4-methoxybenzenesulfonyl)piperazin-1-yl]ethan-1-one (CAS 925397-35-9)
- methyl 4-formylquinoline-8-carboxylate (CAS 2059938-40-6)
- N-(4-Amino-2-chlorophenyl)cyclopentanecarboxamide (CAS 926267-68-7)
- (S)-2-(3,5-dibromophenyl)pyrrolidine (CAS 1241679-43-5)
- 5-Ethynyl-2-fluorobenzaldehyde (CAS 1440535-11-4)
- Palmitoyl Tripeptide-5 TFA (CAS 623172-55-4（free base）)
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