N-(4-chlorophenyl)-2-(3-(pyridin-3-yl)-4,5-dihydroisoxazole-5-carbonyl)hydrazine-1-carboxamide CAS 478064-66-3
| CAS No. | 478064-66-3 |
| Molecular Formula | C16H14ClN5O3 |
| Molecular Weight | 359.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-chlorophenyl)-2-(3-(pyridin-3-yl)-4,5-dihydroisoxazole-5-carbonyl)hydrazine-1-carboxamide.
N-(4-chlorophenyl)-2-(3-(pyridin-3-yl)-4,5-dihydroisoxazole-5-carbonyl)hydrazine-1-carboxamide (CAS 478064-66-3), molecular formula C16H14ClN5O3 and molecular weight 359.77 g/mol, is a CATO reference standard with documented purity and traceability.
N-(4-chlorophenyl)-2-(3-(pyridin-3-yl)-4,5-dihydroisoxazole-5-carbonyl)hydrazine-1-carboxamide (C16H14ClN5O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(4-chlorophenyl)-2-(3-(pyridin-3-yl)-4,5-dihydroisoxazole-5-carbonyl)hydrazine-1-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14ClN5O3 |
| Molecular Weight | 359.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related N Standards
- N-(2-chlorophenyl)-2-(3-(pyridin-3-yl)-4,5-dihydroisoxazole-5-carbonyl)hydrazine-1-carboxamide (CAS 478078-22-7)
- 4-(4-Chlorophenyl)-1-(2,6-dinitrophenyl)-1,2,3,6-tetrahydropyridine (CAS 866150-99-4)
- N-(5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-3,4-dimethoxybenzamide (CAS 865249-44-1)
- 1-[(4-chlorophenyl)carbonyl]-3-[5-(trifluoromethyl)pyridin-2-yl]thiourea (CAS 1353878-23-5)
- 4-(((4-Chlorophenyl)sulfonamido)methyl)-5,5,5-trifluoropentanoic acid (CAS 321970-80-3)
- N-(4-chlorophenyl)-1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxamide (CAS 477886-36-5)
- 3-(4-(2-(3-Chlorophenyl)-2-oxoethyl)phenyl)-5-(methoxymethyl)oxazolidin-2-one (CAS 79039-02-4)
- Ethyl ((3-chlorophenyl)(4-oxochroman-3-yl)methyl)carbamate (CAS 439111-08-7)
Recommended Standards
- Methyl 5-chloro-6-cyclopropyl-1-(2-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011398-22-3)
- Midazolam Impurity 19 (CAS CATO-C4X-150919)
- Methyl 5-chloro-6-cyclopropyl-1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011399-65-7)
- N-(5-Chloro-2-methoxyphenyl)-2-(3-(furan-2-yl)-6-oxopyridazin-1(6H)-yl)acetamide (CAS 879055-07-9)
- 2-(3-Oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carbonyl)-N-{[3-(trifluoromethyl)phenyl]methyl}benzamide (CAS 861209-40-7)
- 2-(Pyrimidin-2-yl)thiazole-5-carbaldehyde (CAS 1235474-02-8)
- Methyl 3-methoxy-5-methylthiophene-2-carboxylate (CAS 181063-59-2)
- 2,5-Dimethyl-1-[4-(trifluoromethyl)phenyl]-1H-pyrrole (CAS 570-05-8)
- N-(2,5-difluorophenyl)thietan-3-amine (CAS 1859272-01-7)
- (3R,3aS,9bS)-9b-((4-Fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalen-3-amine (CAS 2226318-82-5)
- 1-(Tert-butyl)-3-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea (CAS 2246878-24-8)
- Fenoterol EP Impurity C(Enantiomer Mixture) HBr (CAS 2469196-23-2)
- 2-((4-Ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(naphthalen-1-yl)acetamide (CAS 333418-45-4)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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