N-(p-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide CAS 478065-84-8

Purity 97%+In StockPharmaceutical Standards
CAS No.478065-84-8
Molecular FormulaC18H16F3N3O
Molecular Weight347.33 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(p-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide CAS 478065-84-8 chemical structure

Description

The occurrence of N-(p-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies N-(p-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide (CAS 478065-84-8), a certified reference material (molecular formula C18H16F3N3O, MW 347.33 g/mol) for analytical method development and quality control.

The molecular framework of N-(p-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide (C18H16F3N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), N-(p-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H16F3N3O
Molecular Weight347.33 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms3

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