N-(o-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide CAS 866049-66-3

Purity 97%+In StockPharmaceutical Standards
CAS No.866049-66-3
Molecular FormulaC18H16F3N3O
Molecular Weight347.33 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(o-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide CAS 866049-66-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(o-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide.

CATO supplies N-(o-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide (CAS 866049-66-3), a certified reference material (molecular formula C18H16F3N3O, MW 347.33 g/mol) for analytical method development and quality control.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, N-(o-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 347.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(o-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H16F3N3O
Molecular Weight347.33 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms3

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