Sitagliptin Impurity 26 CAS 1402569-71-4
| CAS No. | 1402569-71-4 |
| Molecular Formula | C16H20F3NO4 |
| Molecular Weight | 347.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Sitagliptin Impurity 26 (CAS 1402569-71-4), a pharmacopoeial impurity reference standard (molecular formula C16H20F3NO4, MW 347.33 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C16H20F3NO4, Sitagliptin Impurity 26 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 347.33 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Sitagliptin Impurity 26 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H20F3NO4 |
| Molecular Weight | 347.33 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Sitagliptin Standards
- Sitagliptin Impurity 154 (CAS 2749805-70-5)
- Sitagliptin Impurity 39 (CAS CATO-C4X-1144139)
- Sitagliptin Impurity 124 (CAS CATO-C4X-1144124)
- Sitagliptin Impurity 18 (CAS 922178-94-7)
- Sitagliptin Impurity 28 (CAS 486460-00-8)
- Sitagliptin Impurity 65 (CAS 1620129-74-9)
- Sitagliptin Impurity 83 (CAS 1574485-30-5)
- Sitagliptin Impurity 3 (CAS CATO-C4X-11443)
Recommended Standards
- N-(p-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide (CAS 478065-84-8)
- Fluvoxamine Impurity 34 (CAS CATO-C4X-195134)
- N-(o-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide (CAS 866049-66-3)
- Methyl 1-(4-fluorophenyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011398-72-3)
- Atracurium EP Impurity K (CAS CATO-C4X-185057)
- Esaxerenone Impurity 5 (CAS CATO-C4X-34485)
- Revefenacin Impurity 13 (CAS 864760-28-1)
- N-{2-[(ethylcarbamoyl)amino]ethyl}-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 338404-64-1)
- Methyl 6-nitro-2-oxo-2H-chromene-3-carboxylate (CAS 91059-67-5)
- 4-Benzoylphenyl Methacrylate (CAS 56467-43-7)
- 2-Bromo-5-ethylpyrazine (CAS 1086382-74-2)
- 4'-Nitro-[1,1'-biphenyl]-4-amine (CAS 1211-40-1)
- Methyl 2-(7-Bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-oxoacetate (CAS 954215-11-3)
- Semaglutide impurity 247 (CAS CATO-C4X-2226247)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com