1-(4-Chlorophenyl)-3-(4-ethyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazol-3-yl)pyridazin-4(1H)-one CAS 478077-63-3
| CAS No. | 478077-63-3 |
| Molecular Formula | C22H17ClF3N5OS |
| Molecular Weight | 491.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Chlorophenyl)-3-(4-ethyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazol-3-yl)pyridazin-4(1H)-one.
1-(4-Chlorophenyl)-3-(4-ethyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazol-3-yl)pyridazin-4(1H)-one (CAS 478077-63-3) is a high-purity analytical reference standard with the molecular formula C22H17ClF3N5OS and a molecular weight of 491.92 g/mol.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 1-(4-Chlorophenyl)-3-(4-ethyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazol-3-yl)pyridazin-4(1H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 491.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(4-Chlorophenyl)-3-(4-ethyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazol-3-yl)pyridazin-4(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H17ClF3N5OS |
| Molecular Weight | 491.92 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 3-[(4-Chlorophenyl)methanesulfinyl]-4-phenyl-5-{[3-(trifluoromethyl)phenoxy]methyl}-4H-1,2,4-triazole (CAS 956159-47-0)
- 3-((4-Chlorophenyl)sulfonyl)-2-imino-10-methyl-1-(pyridin-3-ylmethyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 577987-20-3)
- 5-((4-Chlorophenyl)thio)-4-(((2,6-dichlorophenyl)thio)methyl)-1-methyl-3-phenyl-1H-pyrazole (CAS 318951-85-8)
- 2-((6R)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetamide (CAS 1983196-25-3)
- 1-(4-Chlorophenyl)-3-[5-phenyl-1-(2,4,6-trichlorophenyl)-1H-pyrazol-4-yl]urea (CAS 956370-74-4)
- (5E)-3-(2-Chlorophenyl)-5-{[4-(cyclohexylsulfanyl)-3-nitrophenyl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 298215-94-8)
- (5Z)-3-(2-Chlorophenyl)-5-{[2-(cyclohexylsulfanyl)-5-nitrophenyl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 298215-87-9)
- 4-[(4-Chlorophenyl)methanesulfonyl]-2-[(4-methylphenyl)methanesulfonyl]-5,6,7,8-tetrahydroquinazoline (CAS 478049-58-0)
Recommended Standards
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-(N,N-dimethylsulfamoyl)phenyl)piperazine-1-carboxamide (CAS 692733-09-8)
- 5-[(5-chloro-1,3-dimethyl-1H-pyrazol-4-yl)sulphonyl]-4-[4-(trifluoromethoxy)phenyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine (CAS 255872-73-2)
- Rimegepant Impurity 81 (CAS CATO-C4X-248781)
- 4-(4-(Benzyloxy)-2-methylbenzoyl)-5-(4-chlorophenyl)-3-hydroxy-1-(2-methoxyethyl)-1H-pyrrol-2(5H)-one (CAS 489416-77-5)
- (4-Methoxyphenyl)(2-methoxypyrimidin-5-yl)methanamine (CAS 1956376-57-0)
- (5-((tert-Butoxycarbonyl)amino)pyridin-3-yl)boronic acid (CAS 1708122-98-8)
- (1R,3r)-3-(3-fluoro-4-(trifluoromethoxy)phenoxy)cyclobutan-1-amine hydrochloride (CAS 1630907-37-7)
- 8-Chloro-4-hydrazinylquinoline hydrochloride (CAS 1170966-61-6)
- (1-(4-Chloro-3-fluorophenyl)cyclobutyl)methanamine (CAS 1541027-06-8)
- (3-((3S,4S)-4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-6-(2,3-dichlorophenyl)-5-methylpyrazin-2-yl)methanol (CAS 2172651-73-7)
- (3-Fluoro-5-(4-methyl-1H-imidazol-1-yl)phenyl)boronic acid (CAS 2225155-55-3)
- (5-(Aminomethyl)thiophen-2-yl)(phenyl)methanol (CAS 1447963-63-4)
- 2-(Difluoromethyl)-3-hydroxy-5-methoxypyridine-4-carboxaldehyde (CAS 1806942-05-1)
- Hepcidin/LEAP-1 (Human); Liver-Expressed Antimicrobial Peptide (CAS 342790-21-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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