Fluticasone Impurity 50 CAS CATO-C4X-165050
| CAS No. | CATO-C4X-165050 |
| Molecular Formula | C27H31FO7 |
| Molecular Weight | 486.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Fluticasone Impurity 50 (C27H31FO7) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Fluticasone Impurity 50 (CAS CATO-C4X-165050) is a certified pharmaceutical impurity reference standard with the molecular formula C27H31FO7 and a molecular weight of 486.53 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H31FO7 |
| Molecular Weight | 486.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Fluticasone Standards
- Fluticasone Furoate EP Impurity B (CAS 80474-24-4)
- Fluticasone Impurity 39 (CAS CATO-C4X-165039)
- Fluticasone Propionate Dithioacid (CAS CATO-C4X-165047)
- Fluticasone Propionate EP Impurity B (CAS 948566-12-9)
- Fluticasone Propionate Fluoromethyl Ester Analog (CAS 1174034-79-7)
- Fluticasone Impurity 98 (CAS 709002-84-6)
- Fluticasone Propionate EP Impurity D (CAS 73205-13-7)
- Fluticasone Furoate EP Impurity A (CAS 397864-63-0)
Recommended Standards
- Olmesartan Impurity 116 (CAS 3092204-98-0)
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- Benzhydryl 2-(triphenyl-$l^{5}-phosphanyl)acetate (CAS 61042-29-3)
- Vonoprazan Fumarate Impurity 83 (CAS 928325-41-1 (free base))
- Gadoteridol Impurity 24 (CAS CATO-C4X-225724)
- Loxoprofen impurity 120 (CAS CATO-C4X-1488120)
- γ-Chaconine (CAS 511-36-4)
- 2-(3-Amino-4-hydroxyphenyl)acetic acid (CAS 38196-08-6)
- Clonazepam impurity 10 (CAS CATO-C4X-140310)
- Ulipristal Impurity 29 (CAS 1655514-78-5)
- 1-(3-bromo-1-methyl-1H-pyrazol-5-yl)-2-(morpholin-4-yl)ethan-1-ol (CAS 2145694-89-7)
- 2-amino-1-(1-methylcyclopentyl)ethan-1-one hydrochloride (CAS 2044722-83-8)
- Insulin Degludec Impurity 6 (CAS CATO-C4X-21576)
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