Edoxaban Impurity N77 CAS 480449-84-1
| CAS No. | 480449-84-1 |
| Molecular Formula | C14H26N2O4 |
| Molecular Weight | 286.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Edoxaban Impurity N77 is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Edoxaban Impurity N77 (CAS 480449-84-1) is a certified pharmaceutical impurity reference standard with the molecular formula C14H26N2O4 and a molecular weight of 286.37 g/mol.
Edoxaban Impurity N77 (C14H26N2O4) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Edoxaban Impurity N77 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H26N2O4 |
| Molecular Weight | 286.37 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Edoxaban Standards
- Edoxaban Impurity 54 (1S,3R,4R) (CAS 1392745-59-3)
- Edoxaban Impurity 63 (CAS 929693-30-1)
- Edoxaban Impurity 47 (CAS 1210348-16-5)
- Edoxaban Impurity 58 (1R,3S,4R) (CAS 1392745-22-0)
- Edoxaban Impurity 1 (CAS 1392745-43-5)
- Edoxaban Impurity N3 (CAS 1392745-70-8)
- Edoxaban Impurity N46 (CAS 1353893-25-0)
- Edoxaban Impurity N47 (CAS 365997-33-7)
Recommended Standards
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- Bumetanide Impurity 5 (CAS 22892-96-2)
- Ruxolitinib Impurity 1 (CAS 2606144-44-7)
- Brivaracetam impurity 102 (CAS CATO-C4X-2007102)
- 4,4'-(Propane-2,2-diyl)bis(2-methyl-1-(octyloxy)benzene) (CAS 2173992-24-8)
- 1-(2-fluoro-3-methoxyphenyl)cyclopropan-1-amine hydrochloride (CAS 1909320-05-3)
- (E)-3-oxo-2-phenylbutanal O-(3-(trifluoromethyl)benzyl) oxime (CAS 339116-05-1)
- 3',5',6',7'-Tetrahydrospiro[cyclobutane-1,4'-imidazo[4,5-c]pyridin]-7'-ol (CAS 2138255-51-1)
- 2-Bromo-3-cyano-5-fluorobenzoic acid (CAS 1805590-57-1)
- Mabuterol (CAS 56341-08-3)
- Peptide WE-14 (CAS 115136-18-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com