Bumetanide Impurity 5 CAS 22892-96-2
| CAS No. | 22892-96-2 |
| Molecular Formula | C7H5ClN2O6S |
| Molecular Weight | 280.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Bumetanide Impurity 5 (C7H5ClN2O6S) is characterized by a carbohydrate-derived structure, an amide group, a sulfone group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Bumetanide Impurity 5 (CAS 22892-96-2) is a certified pharmaceutical impurity reference standard with the molecular formula C7H5ClN2O6S and a molecular weight of 280.64 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Bumetanide Impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN2O6S |
| Molecular Weight | 280.64 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bumetanide Standards
- Bumetanide Impurity 45 (CAS 61658-42-2)
- Bumetanide Impurity 133 (CAS CATO-C4X-1986133)
- Bumetanide Impurity 48 (CAS CATO-C4X-198648)
- Bumetanide Impurity 80 (CAS CATO-C4X-198680)
- Bumetanide Impurity 73 (CAS CATO-C4X-198673)
- Bumetanide Impurity 7 (CAS 130262-91-8)
- Bumetanide Impurity 40 (CAS 688047-82-7)
- Bumetanide Impurity 78 (CAS CATO-C4X-198678)
Recommended Standards
- 2-Chloro-N-(4,5,6-trifluoro-1,3-benzothiazol-2-yl)acetamide (CAS 379255-48-8)
- 3-Chloro-6-(trifluoromethyl)benzo[b]thiophene-2-carboxylic acid (CAS 923849-73-4)
- 7-Chloro-3-(methoxycarbonyl)-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (CAS 170143-39-2)
- 5-Chloro-3-trifluoromethylbenzo[b]thiophene-2-carboxylic acid (CAS 752135-60-7)
- Vortioxetine Impurity 35 (CAS 1293489-69-6)
- Piperacillin EP Impurity E (CAS 59702-31-7)
- Osimertinib Impurity 110 (CAS CATO-C4X-2045110)
- Tert-butyl (1-benzyl-2,5-dimethylpiperidin-3-yl)carbamate (CAS 1315365-51-5)
- 2-Anilinoisonicotinic acid (CAS 1019461-36-9)
- n-Methyl-1-(5-methyl-4-phenyl-4h-1,2,4-triazol-3-yl)methanamine (CAS 1249003-45-9)
- (2-((2-Methylallyl)oxy)phenyl)methanol (CAS 120368-15-2)
- 3-[(prop-2-en-1-yl)sulfamoyl]benzoic acid (CAS 500292-31-9)
- 3-((4-(4-Chlorophenyl)piperazin-1-yl)methyl)-1H-pyrrolo[2,3-b]pyridine trihydrochloride (CAS 158985-00-3)
- D-Pro38-Tirzepatide (CAS CATO-CPTD788901)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com