Edoxaban Impurity 85 CAS 480451-97-6
| CAS No. | 480451-97-6 |
| Molecular Formula | C14H25N5O3 |
| Molecular Weight | 311.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Edoxaban Impurity 85 (CAS 480451-97-6, C14H25N5O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Edoxaban Impurity 85 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 311.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H25N5O3 |
| Molecular Weight | 311.38 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 5 |
Related Edoxaban Standards
- Edoxaban Impurity 35 (CAS 480450-69-9)
- Edoxaban Impurity 33 (CAS 349125-14-0)
- Edoxaban Impurity 74 (CAS 1210348-21-2)
- Edoxaban Impurity N37 (CAS 365997-34-8)
- Edoxaban Impurity 86 (CAS CATO-C4X-106386)
- Edoxaban Impurity 8 (CAS CATO-C4X-10638)
- Edoxaban Impurity 32 (CAS 1461714-66-8)
- Edoxaban Impurity 47 (CAS 1210348-16-5)
Recommended Standards
- Sildenafil Impurity 31 (CAS CATO-C4X-112831)
- (E)-N-(2-aminoethyl)-4-((4-(dimethylamino)phenyl)diazenyl)benzamide (CAS CATO-C3D-262866)
- Anastrozole Impurity 8 (CAS CATO-C4X-12398)
- 4-(3-hydroxybenzyl)-N-(pyridin-3-yl)piperidine-1-carboxamide (CAS CATO-C3D-262394)
- Baloxavir Marboxil Impurity 240 (CAS CATO-C4X-2108240)
- Asenapine Impurity 10 (CAS CATO-C4X-194710)
- Bisacodyl EP Impurity B (CAS 16985-05-0)
- 2-Bromo-3-methyl-5H-pyrrolo[2,3-b]pyrazine (CAS 1260812-97-2)
- Ethyl 3-(2,6-dichlorobenzyl)-1,2,4-oxadiazole-5-carboxylate (CAS 1246056-08-5)
- 2-Fluoro-4,5-dimethoxybenzene-1-sulfonyl chloride (CAS 656806-43-8)
- Finerenone Impurity 156 (CAS CATO-C4X-2880156)
- 3-(2-Chlorophenyl)butan-2-amine hydrochloride (CAS 21900-00-5)
- N-(4-Cyanophenyl)-3,4-difluorobenzamide (CAS 1007802-68-7)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
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