Benserazide Impurity 19 CAS 487-70-7
| CAS No. | 487-70-7 |
| Molecular Formula | C7H6O4 |
| Molecular Weight | 154.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Benserazide Impurity 19 (C7H6O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Benserazide Impurity 19 (CAS 487-70-7, C7H6O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Benserazide Impurity 19 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6O4 |
| Molecular Weight | 154.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Benserazide Standards
- Benserazide Impurity 18 (CAS 2144-08-3)
- Benserazide Impurity 20 (CAS 35094-87-2)
- Benserazide Impurity 22 (CAS 13677-79-7)
- Benserazide Impurity 31 (CAS 437988-46-0)
- Benserazide Impurity 53 (CAS 773868-38-5)
- Benserazide Impurity 32 (CAS 3955-29-1)
- Benserazide Impurity 59 (CAS CATO-C4X-142759)
- Benserazide Impurity 21 (CAS 5625-41-2)
Recommended Standards
- Mesalazine EP Impurity G (CAS 490-79-9)
- Terbutaline EP Impurity A (CAS 99-10-5)
- Acipimox (CAS 51037-30-0)
- 2,3-Dihydroxybenzoic Acid (CAS 303-38-8)
- Mirabegron Impurity 141 (CAS CATO-C4X-1032141)
- Epinastine Impurity 28 (CAS 532-55-8)
- Macitentan Impurity 24 (CAS 556797-16-1)
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