2-(2-Chlorophenyl)-3-(4-fluorobenzoyl)oxirane CAS 497181-17-6
| CAS No. | 497181-17-6 |
| Molecular Formula | C15H10ClFO2 |
| Molecular Weight | 276.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(2-Chlorophenyl)-3-(4-fluorobenzoyl)oxirane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(2-Chlorophenyl)-3-(4-fluorobenzoyl)oxirane (CAS 497181-17-6), molecular formula C15H10ClFO2 and molecular weight 276.69 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(2-Chlorophenyl)-3-(4-fluorobenzoyl)oxirane (C15H10ClFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 276.69 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H10ClFO2 |
| Molecular Weight | 276.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Chlorophenyl Standards
- 2-(((4-Chlorophenyl)thio)difluoromethyl)-5-methyl-1,3,4-oxadiazole (CAS 1403565-95-6)
- (2E)-2-[2-(4-Chlorophenyl)hydrazin-1-ylidene]-3-(furan-2-yl)-3-oxopropanal (CAS 338400-29-6)
- N-(2-chlorophenyl)-2-nitrobenzamide (CAS 50622-99-6)
- N-(2-chlorophenyl)-4-nitrobenzamide (CAS 2585-28-6)
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- n-(4-Chlorophenyl)-2-nitrobenzamide (CAS 41562-57-6)
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Recommended Standards
- 2-(2-Chloro-6-fluorophenyl)-2,3-dihydroquinazolin-4(1H)-one (CAS 883032-29-9)
- 2-(Chloromethyl)-1-isopropyl-5-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 942035-03-2)
- (2e)-3-[3-(chlorosulfonyl)-4-methoxyphenyl]prop-2-enoic acid (CAS 610258-89-4)
- 3-(4-Chloro-phenyl)-2-(4-fluoro-phenyl)-acrylic acid (CAS 377769-45-4)
- 1-(3-chloro-4-methylphenyl)-5-pyridin-4-yl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1326859-69-1)
- 4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one 804551-71-1 CHIR-258 Chir 258 D07OZR TKI-258 TKI-258, Dovitinib, CHIR258, TKI258 TKI258 (CAS 804551-71-1)
- 2-(2-Chlorobenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1365565-86-1)
- 4-(Tert-butoxy)butan-1-amine (CAS 100364-13-4)
- 1-(((9H-fluoren-9-yl)methoxy)carbonyl)-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid (CAS 1822498-26-9)
- N-((3,3-difluorocyclobutyl)methyl)thietan-3-amine (CAS 1872644-18-2)
- 1-Bromo-4-ethoxy-2-fluoro-5-methoxybenzene (CAS 1095544-33-4)
- 2-(2-Chlorobenzamido)-3-hydroxybutanoic acid (CAS 1008206-36-7)
- 2,2-Dimethyl-4-piperidone Hydrochloride (CAS 1303968-37-7)
- Mast Cell Degranulating Peptide (CAS 83856-13-7)
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