2-(((1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)amino)ethane-1-sulfonic acid CAS 497258-54-5
| CAS No. | 497258-54-5 |
| Molecular Formula | C12H19N3O8S2 |
| Molecular Weight | 397.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(((1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)amino)ethane-1-sulfonic acid.
2-(((1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)amino)ethane-1-sulfonic acid (CAS 497258-54-5) is a high-purity analytical reference standard with the molecular formula C12H19N3O8S2 and a molecular weight of 397.42 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 2-(((1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)amino)ethane-1-sulfonic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 397.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H19N3O8S2 |
| Molecular Weight | 397.42 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Recommended Standards
- Fmoc-D-Cit-OH (CAS 200344-33-8)
- Dolutegravir Impurity 46 (CAS 2244245-34-7)
- Fmoc-CIT-OH (CAS 133174-15-9)
- Dolutegravir Impurity 50 (CAS CATO-C4X-162050)
- 1-(Chloromethyl)-1-propylcyclopropane (CAS 1481389-10-9)
- 5-(2-(1-Fluoro-2-methylpropan-2-yl)pyrimidin-4-yl)-4-methylthiazol-2-amine (CAS 1217487-70-1)
- rac Rasagiline-13C3 Mesylate (CAS 1216757-55-9)
- {6,8-dichloroimidazo[1,2-a]pyridin-2-yl}methanol (CAS 1235441-30-1)
- 1-(2-(Benzyloxy)-4-fluorophenyl)ethanone (CAS 106245-03-8)
- 7-Oxohexadecanoic acid (CAS 54527-29-6)
- 5,7-dibromo-[1,2,4]triazolo[1,5-a]pyridine (CAS 2306270-61-9)
- 7-Hydroxybenzofuran-5-carbonitrile (CAS 2090472-33-4)
- Ranitidine Impurity 10 (CAS 113224-25-2)
- Fibrinopeptide A (human) (CAS 25422-31-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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