Dolutegravir Impurity 50 CAS CATO-C4X-162050
| CAS No. | CATO-C4X-162050 |
| Molecular Formula | C21H23N3O5 |
| Molecular Weight | 397.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 397.42 g/mol gives Dolutegravir Impurity 50 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Dolutegravir Impurity 50 (CAS CATO-C4X-162050) is a certified pharmaceutical impurity reference standard with the molecular formula C21H23N3O5 and a molecular weight of 397.42 g/mol.
Dolutegravir Impurity 50 (C21H23N3O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Dolutegravir Impurity 50 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H23N3O5 |
| Molecular Weight | 397.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Dolutegravir Standards
- Dolutegravir Impurity 46 (CAS 2244245-34-7)
- Dolutegravir Impurity 28 (CAS 1646862-09-0)
- Dolutegravir Impurity 8 (CAS 1863916-88-4)
- Dolutegravir Impurity 9 (CAS 1863916-87-3)
- Dolutegravir Impurity 23 (CAS CATO-C4X-162023)
- Dolutegravir Impurity 31 (CAS CATO-C4X-162031)
- Dolutegravir Impurity 48 (CAS CATO-C4X-162048)
- Dolutegravir Impurity 53 (CAS CATO-C4X-162053)
Recommended Standards
- Finerenone Impurity 39 (CAS CATO-C4X-288039)
- 2-(((1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)amino)ethane-1-sulfonic acid (CAS 497258-54-5)
- Finerenone Impurity 43 (CAS CATO-C4X-288043)
- Fmoc-D-Cit-OH (CAS 200344-33-8)
- Fosfomycin Impurity 28 (CAS CATO-C4X-131628)
- Orforglipron impurity 135 (CAS 2384281-38-1)
- Posaconazole Impurity 102 (CAS CATO-C4X-1208102)
- Methyl 2-(2-(2-(4,6-dimethylpyrimidin-2-yl)hydrazono)-4-oxo-3-phenylthiazolidin-5-ylidene)acetate (CAS 890630-63-4)
- 3-(chloromethyl)-2-fluoro-pyridine (CAS 315180-14-4)
- Naphthalenesulfonic acid, sodium salt (CAS 1321-69-3)
- (S)-2-((Ethylthio)methyl)furan-3(2H)-one (CAS 92544-23-5)
- methyl 4-[(6-cyanopyridin-3-yl)oxy]benzoate (CAS 1547789-81-0)
- 2,3-Difluoro-6-hydroxy-5-methylbenzaldehyde (CAS 704884-75-3)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
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