Methyl 7-bromo-1-propyl-2,3-dihydro-1H-benzo[b]azepine-4-carboxylate CAS 497856-41-4
| CAS No. | 497856-41-4 |
| Molecular Formula | C15H18BrNO2 |
| Molecular Weight | 324.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 7-bromo-1-propyl-2,3-dihydro-1H-benzo[b]azepine-4-carboxylate (CAS 497856-41-4), molecular formula C15H18BrNO2 and molecular weight 324.21 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, Methyl 7-bromo-1-propyl-2,3-dihydro-1H-benzo[b]azepine-4-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 324.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H18BrNO2 |
| Molecular Weight | 324.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- N'-(1-(2,4-Dichlorophenyl)ethylidene)-2-(1-methyl-1H-pyrrol-2-yl)acetohydrazide (CAS 315226-16-5)
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- 4-(Bromomethyl)-N-(tert-butyl)-2-fluorobenzenesulfonamide (CAS 415679-06-0)
- Tert-butyl 6-bromo-1,1a,2,7b-tetrahydro-3H-cyclopropa[c]quinoline-3-carboxylate (CAS 2417969-69-6)
- 4-Phenyl-3-buten-2-amine (CAS 53309-95-8)
- 4-Bromo-2-(difluoromethyl)-3-hydroxypyridine-6-carbonyl chloride (CAS 1805372-74-0)
- (S)-2-Amino-5-butyrimidamidopentanoic acid hydrochloride (CAS 150403-97-7)
- 3,5-Dibromo-2-fluoro-6-iodobenzoic acid (CAS 1160573-45-4)
- 8-Bromo-7-chloroimidazo[1,2-a]pyridine (CAS 1357945-16-4)
- 2,4-Diphenyl-5-[(Z)-2-phenyldiazen-1-yl]pyrimidine (CAS 339279-49-1)
- (4-Fluoro-1H-indol-2-yl)methanamine (CAS 904885-13-8)
- 2-Bromo-4-morpholinobenzonitrile (CAS 1129540-63-1)
- Ioversol Impurity 1 (CAS 134768-85-7)
- Semaglutide impurity 249 (CAS CATO-C4X-2226249)
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