Lurbinectedin Impurity 21 CAS 497871-67-7
| CAS No. | 497871-67-7 |
| Molecular Formula | C43H46N4O9S |
| Molecular Weight | 794.91 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Lurbinectedin Impurity 21 (CAS 497871-67-7, C43H46N4O9S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lurbinectedin Impurity 21 (C43H46N4O9S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Lurbinectedin Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C43H46N4O9S |
| Molecular Weight | 794.91 g/mol |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 23.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Lurbinectedin Standards
- Lurbinectedin Impurity 2 (CAS 497871-10-0)
- Lurbinectedin Impurity 3 (CAS CATO-C4X-31143)
- Lurbinectedin Impurity 34 (CAS CATO-C4X-311434)
- Lurbinectedin Impurity 7 (CAS CATO-C4X-31147)
- Lurbinectedin Impurity 9 (CAS CATO-C4X-31149)
- Lurbinectedin Impurity 13 (CAS CATO-C4X-311413)
- Lurbinectedin (CAS 497871-47-3)
- Lurbinectedin Impurity 27 (CAS 2749898-64-2)
Recommended Standards
- (-)-Conophylline (CAS 142741-24-0)
- O-Benzyl Posaconazole-d4 (CAS 1246818-95-0)
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- Rifapentine impurity 15 (CAS CATO-C4X-195915)
- Domperidone EP Impurity F (CAS 1391053-55-6)
- Lasmiditan Impurity 25 (CAS CATO-C4X-247825)
- Carboplatin EP Impurity B Disilver Salt (CAS 1933502-35-2)
- Methyl 4-Fluorobenzo[b]thiophene-2-carboxylate (CAS 220180-55-2)
- Methyl 1-(2-(5-(4-methoxyphenyl)isoxazol-3-yl)acetyl)piperidine-4-carboxylate (CAS 952986-95-7)
- 1-Allyl-5-oxopyrrolidine-3-carbohydrazide (CAS 1437312-07-6)
- Glumetinib Impurity 13 (CAS CATO-C4X-325913)
- 4-Cyclobutylphenol (CAS 10292-59-8)
- 4-Chloro-6-ethyl-5-methylpyrimidine (CAS 144078-60-4)
- 3AEEA-Semaglutide(Endo-AEEA-Semaglutide) (CAS CATO-C4X-2226265)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com